Evidence map›Paper›PMID 35487602›Full record

ReviewClinics in liver disease2022

Hyponatremia in Cirrhosis.

Helbert Rondon-Berrios, Juan Carlos Q Velez

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in liver disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  12. Review
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  14. Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Helbert Rondon-BerriosDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh School of Medicine, 3550 Terrace Street, A915 Scaife Hall, Pittsburgh, PA 15261, USA. Electronic address: rondonberriosh@upmc.edu.
Juan Carlos Q VelezDepartment of Nephrology, Ochsner Health, 1514 Jefferson Highway, Clinic Tower 5th, Floor, Room 5E328, New Orleans, LA 70121, USA; Ochsner Clinical School/The University of Queensland, Brisbane, Queensland, Australia. Electronic address: https://twitter.com/VelezNephHepato.
University of Pittsburgh · USUniversity of Queensland · AU

Funding

Urea for chronic hyponatremia: a pilot studyR21DK122023 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RONDON BERRIOS, HELBERT, WEISBORD, STEVEN · 2020 to 2021
$430k
NIDDK NIH HHS R21 DK122023
6 · The paper itself

Abstract

Hyponatremia is the most common electrolyte disorder encountered in clinical practice, and it is a common complication of cirrhosis reflecting an increase in nonosmotic secretion of arginine vasopressin as a result of of the circulatory dysfunction that is characteristic of advanced liver disease. Hyponatremia in cirrhosis has been associated with poor clinical outcomes including increased risk of morbidity and mortality, poor quality of life, and heightened health care utilization. Despite this, the treatment of hyponatremia in cirrhosis remains challenging as conventional therapies such as fluid restriction are frequently ineffective. In this review, we discuss the epidemiology, clinical outcomes, pathogenesis, etiology, evaluation, and management of hyponatremia in cirrhosis.

Indexed as

HyponatremiaHumansLiver CirrhosisQuality of LifeAlbuminArginine vasopressinAscitesCentral pontine myelinolysisCirrhosisHyponatremiaLiver transplantationOsmotic demyelination syndrome

Identifiers

PMID35487602
PMCPMC9060324
OpenAlexW4220830032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.