Evidence map›Paper›PMID 35487563›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 1: Technical Considerations and Perfusion and Neuronal Imaging.

John C Stendahl, Jennifer M Kwan, Darko Pucar, Mehran M Sadeghi

Open access · greenAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

John C StendahlSection of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut.
Jennifer M KwanSection of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut.
Darko PucarDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; and.
Mehran M SadeghiSection of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut; mehran.sadeghi@yale.edu.
Yale University · USVA Connecticut Healthcare System · US

Funding

PET Imaging of MMP Activation in AAA: First in-Human EvaluationR01AG065917 · NIA · YALE UNIVERSITY · PI GROPLER, ROBERT J., SADEGHI, MEHRAN M · 2020 to 2024
$3.3M
Novel Regulators of Calcific Aortic Valve DiseaseR01HL138567 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2017 to 2020
$2.8M
Targeted delivery of nanomedicines to the coronary microvasculature during ex vivo normothermic perfusion of marginal human heartsK08HL155888 · NHLBI · YALE UNIVERSITY · PI John C Stendahl · 2022 to 2026
$811k
Mechanistic studies of disease progression in aortic aneurysmsI01BX004038 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI SADEGHI, MEHRAN M · 2019 to 2022
–
BLRD VA I01 BX004038NHLBI NIH HHS K08 HL155888NHLBI NIH HHS R01 HL138567NIA NIH HHS R01 AG065917
6 · The paper itself

Abstract

The development of new radiotracers for PET and SPECT is central to addressing unmet diagnostic needs related to systemwide trends toward molecular characterization and personalized therapies in cardiovascular medicine. In the following 2-part review, we discuss select emerging radiotracers that may help address important unmet diagnostic needs in central areas of cardiovascular medicine, such as heart failure, arrhythmias, valvular disease, atherosclerosis, and thrombosis. Part 1 examines key technical considerations pertaining to cardiovascular radiotracer development and reviews emerging radiotracers for perfusion and neuronal imaging. Highlights of this work include discussions on the development of

Indexed as

AtherosclerosisPositron-Emission TomographyHumansPerfusionRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonRadiopharmaceuticalscardiology (basic/technical)cardiology (clinical)inflammationmolecular imagingmyocardial perfusion imaging

Identifiers

PMID35487563
PMCPMC12079752
OpenAlexW4225259208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.