Evidence map›Paper›PMID 35487560›Full record

ArticleGlobal health, science and practice2022

Cost of Delivering Tetanus Toxoid and Tetanus-Diphtheria Vaccination in Vietnam and the Budget Impact of Proposed Changes to the Schedule.

Vu Quynh Mai, Laura Boonstoppel, Kelsey Vaughan, Carl Schutte, Annette Ozaltin, Duong Thi Hong, Nguyen Mai Khanh, Hoang Manh Thang, Tran Tuan Anh, Hoang Van Minh

Open access · diamondAbstract read
In one paragraph

Article in Global health, science and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. The cost of delivering COVID-19 vaccines in Vietnam.BMC health services research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Vu Quynh MaiCenter for Population Health Sciences, Hanoi University of Public Health, Hanoi, Vietnam. vqm@huph.edu.vn.
Laura BoonstoppelThinkWell, Washington, DC, USA.
Kelsey VaughanThinkWell, Washington, DC, USA.
Carl SchutteGenesis Analytics, Johannesburg, South Africa.
Annette OzaltinThinkWell, Washington, DC, USA.
Duong Thi HongNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Nguyen Mai KhanhNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Hoang Manh ThangCenter for Population Health Sciences, Hanoi University of Public Health, Hanoi, Vietnam.
Tran Tuan AnhCenter for Population Health Sciences, Hanoi University of Public Health, Hanoi, Vietnam.
Hoang Van MinhHanoi University of Public Health, Hanoi, Vietnam.
Hanoi School Of Public Health · VNHanoi University · VNNational Institute Of Hygiene And Epidemiology · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn 2017, aligned with global World Health Organization tetanus guidelines, Vietnam prepared evidence to support a recommendation to introduce the tetanus-diphtheria (Td) vaccine into routine immunization. This study aimed to provide evidence on the costs and budgetary impact of the potential replacement of the tetanus-toxoid (TT) vaccine with the Td vaccine, considering different possible delivery strategies.

methodWe used an activity-based ingredients costing approach to estimate the 2017 program costs of providing TT vaccination to girls aged 15-16 years and conducting Td campaigns in outbreak areas. We performed a budget impact analysis for 2018-2025 using the cost per dose estimates based on the current delivery of these vaccines. We assumed complete cessation of TT vaccination of girls aged 15-16 years and a transition period where Td outbreak control campaigns would still occur. Td vaccine was assumed to be provided to children aged 7 years using either facility- or school-based delivery or combined facility- and school-based delivery.

resultsThe delivery cost per dose for current TT vaccination for girls aged 15-16 years was US$1.49 for school-based delivery, US$1.76 for facility-based delivery, and US$3.86 for delivery via outreach. Td vaccination through campaigns was estimated to cost US$3.56/dose. During 2018-2025, replacing the TT vaccine for girls aged 15-16 years with the Td vaccine for children aged 7 years is estimated to save US$4.61 million in immunization delivery costs if a school-based delivery strategy is used or US$1.04 million if facility-based delivery is used.

conclusionCompared to the current plan, delivery of Td routine vaccination via a school-based strategy was the most cost saving. These results were used in late 2019 to support the delivery of Td vaccination using a school-based delivery strategy for children aged 7 years in 30 Northern provinces in Vietnam.

Indexed as

DiphtheriaTetanusChildDiphtheria-Tetanus VaccineFemaleHumansTetanus ToxoidVaccinationVietnamDiphtheria-Tetanus VaccineTetanus Toxoid

Identifiers

PMID35487560
PMCPMC9053159
OpenAlexW4225259872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.