Evidence map›Paper›PMID 35486879›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2022

Mitogen-Activated Protein Kinase Inhibitor Selumetinib Fails to Increase the Complete Response Rate of Radioactive Iodine Alone in High-Risk Differentiated Thyroid Cancer: Lessons From the Phase III ASTRA Study.

Marcia S Brose, Daniel A Pryma, Kate L Newbold

Open access · bronzeAbstract readEditorialComment
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Marcia S BroseDepartment of Medical Oncology, Jefferson University Sidney Kimmel Cancer Center, Philadelphia, PA.ORCID 0000-0001-7096-4057
Daniel A PrymaDepartment of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Kate L NewboldThyroid Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom.
Royal Marsden NHS Foundation Trust · GBSidney Kimmel Cancer Center · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Thyroid NeoplasmsBenzimidazolesClinical Trials, Phase III as TopicHumansIodine RadioisotopesMitogen-Activated Protein KinasesProtein Kinase InhibitorsAZD 6244BenzimidazolesIodine RadioisotopesMitogen-Activated Protein KinasesProtein Kinase Inhibitors

Identifiers

PMID35486879
PMCPMC9177242
OpenAlexW4225094260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.