ArticlePLoS neglected tropical diseases2022
Molecular epidemiology of scrub typhus in Taiwan during 2006-2016.
Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Case Report: An imported severe case of paediatric scrub typhus with Karp B subgenotype in non-endemic Northern China, Beijing.Frontiers in pediatrics · 2026Article
- Beyond the infection: mapping the risk of cardiovascular events post-scrub typhus in a nationwide cohort study.Emerging microbes & infections · 2025Article
- Epidemiological features of scrub typhus and molecular characteristics ofIJID regions · 2025Article
- Utility of next-generation sequencing for the etiological diagnosis ofInfectious medicine · 2024Article
- Concatenated ScaA and TSA56 Surface Antigen Sequences Reflect Genome-Scale Phylogeny ofPathogens (Basel, Switzerland) · 2024Article
- Epidemiology of Murine Typhus in Taiwan from 2013 to 2020.The American journal of tropical medicine and hygiene · 2024Article
- Molecular Detection of Multiple Genotypes ofTropical medicine and infectious disease · 2023Article
- Correction: Molecular epidemiology of scrub typhus in Taiwan during 2006-2016.PLoS neglected tropical diseases · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scrub typhus is the most common endemic vector-borne disease in Taiwan. We identified a total of 4,857 laboratory-confirmed cases during 2006-2016 with hyperendemic foci on offshore islands, including Penghu (778 cases, 16.0%) and Kinmen (716 cases, 14.7%), and eastern Taiwan, including Taitung (628 cases, 12.9%) and Hualien (508 cases, 10.5%). Scrub typhus cases occur year-round throughout Taiwan, with a summer peak in June and July. A total of 545 O. tsutsugamushi isolates were successfully obtained from patients infected in diverse geographic areas, including Taiwan and three offshore islands, and the complete open reading frame of the 56 kDa type-specific antigen gene (tsa56) sequence of these isolates was examined. High phylogenetic diversity was found in these isolates, which could be grouped into 36 distinct sequence types. Most isolates belonged to the Karp (49.9%; 272/545), followed by the TW-22 (17.8%; 97/454) and Kawasaki (14.7%; 80/545) genotypes. In conclusion, our data indicate the widespread presence of tsa56 genotypes closely related to Thailand and Korean strains and the presence of the unique endemic strains TW-12, TW-22, TW-29, and TW-36 in Taiwan.
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