ArticleJournal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
Facial Affect Sensitivity Training for Young Children with Emerging CU Traits: An Experimental Therapeutics Approach.
Article in Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04159168 (Facial Affect Sensitivity Training for Young Children With CU Traits), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Facial Affect Sensitivity Training for Young Children With CU Traits
Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Affective theory of mind impairments linked with callous-unemotional traits implicate cognitive control: A pre-registered double-blind randomized controlled trial with a dual-task paradigm.Journal of affective disorders · 2025Trial
- Treatment Outcomes of Children with Primary Versus Secondary Callous-Unemotional Traits.Research on child and adolescent psychopathology · 2023Trial
- Network Structures of Psychopathy: Unidimensional and Multidimensional Approaches.Personality and individual differences · 2025Article
- Deficits in emotion recognition and processing in children with high callous-unemotional traits: the role of the MAOA gene.European child & adolescent psychiatry · 2024Article
- Associations between Subtypes of Empathy and Aggression in High-Risk Adolescents.Journal of psychopathology and behavioral assessment · 2024Article
- The Emotionally Sensitive Child-Adverse Parenting Experiences-Allostatic (Over)Load (ESCAPE-AL) Model for the Development of Secondary Psychopathic Traits.Clinical child and family psychology review · 2023Article
- Executive function and underlying brain network distinctions for callous-unemotional traits and conduct problems in adolescents.bioRxiv : the preprint server for biology · 2023Article
- Efficiency of Heterogenous Functional Connectomes Explains Variance in Callous-Unemotional Traits After Computational Lesioning of Cortical Midline and Salience Regions.Brain connectivity · 2023Article
- Cognitive Mechanisms Underlying Prosocial Decision Making in Callous-Unemotional Traits.Journal of psychopathology and behavioral assessment · 2023Article
- Affective theory of mind impairments underlying callous-unemotional traits and the role of cognitive control.Cognition & emotionArticle
- How can (or could) biology inform more effective parenting interventions for childhood aggression?Aggression and violent behaviorArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThis article delineates best practices in the application of the experimental therapeutics framework for evaluating interventions within the context of randomized controlled trials (RCTs), offering a methodological primer and guiding framework for this approach. We illustrate these practices using an ongoing clinical trial conducted within the framework of a National Institute of Mental Health exploratory phased-innovation award for the development of psychosocial therapeutic interventions for mental disorders (R61/R33), describing the implementation of a novel "Facial Affect Sensitivity Training" (
methodWe outline the stages, goals, and best practices for an experimental therapeutics framework. In the FAST trial, we assert that impaired sensitivity for emotional distress cues (fear and/or sadness) is mechanistically linked to CU traits in children, and that by targeting sensitivity to facial affect directly via a computerized automated feedback and incentive system, we can exert downstream effects on CU traits.
resultsIn the context of an open pilot trial, we found preliminary support for feasibility and mechanism engagement using
conclusionsWe summarize pilot study limitations and how they are being addressed in the R61/R33 RCTs, as well as challenges and future directions for psychosocial experimental therapeutics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.