Evidence map›Paper›PMID 35486216›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

Criteria for developing, assessing and selecting candidate EQ-5D bolt-ons.

Brendan J Mulhern, Chris Sampson, Phil Haywood, Rebecca Addo, Katie Page, David Mott, Koonal Shah, Mathieu F Janssen, Mike Herdman

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Comparative performance of EQ-5D-5L bolt-ons in China and the Netherlands: results from the EQ-DAPHNIE project.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  4. Article
  5. Measuring inequality in quality of life: further evidence that the EQ-5D-5L may underestimate it.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  6. Psychometric validation of a cognition and social participation bolt-on for the EQ-5D-5L in SARS-CoV-2 infected German healthcare workers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  7. Testing culturally relevant EQ-5D-5L bolt-ons for the Chinese general population: first quantitative phase of a mixed methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  8. Article
  9. Validity of EQ-5D-5L breathing and cognition bolt-ons in non-hospitalized patients after COVID-19.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  10. Article
  11. Review
  12. Identifying and developing culturally relevant EQ-5D-5L bolt-on items for Chinese population: qualitative phase of a mixed-methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  13. Psychometric testing of two respiratory bolt-on items to EQ-5D-5L in patients with obstructive airway diseases.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  14. Psychometric benefits of adding bolt-ons to the EQ-5D-5L in populations undergoing minimally invasive cosmetic procedures.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  15. Developing and testing a patient-reported outcome measure for patients with sleep disturbances using EQ-5D and condition-specific bolt-ons: a mixed method study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  16. Article
  17. Qualitative evidence on EQ-5D-5L skin irritation and self-confidence bolt-ons in Darier's disease and Hailey-Hailey disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  18. Article
  19. Testing the psychometric characteristics of EQ-5D-5L and respiratory bolt-ons using a sample of the Australian population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brendan J MulhernCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia. brendan.mulhern@uts.edu.au.
Chris SampsonOffice of Health Economics, London, UK.
Phil HaywoodCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.
Rebecca AddoCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.
Katie PageCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.
David MottOffice of Health Economics, London, UK.
Koonal ShahPHMR, London, UK.
Mathieu F JanssenEuroQol Research Foundation, Rotterdam, Netherlands.
Mike HerdmanOffice of Health Economics, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose'Bolt-on' dimensions are additional items added to multi-attribute utility instruments (MAUIs) such as EQ-5D that measure constructs not included in the core descriptive system. The use of bolt-ons has been proposed to improve the content validity and responsiveness of the descriptive system in certain settings and health conditions. EQ-5D bolt-ons serve a particular purpose and thus satisfy a certain set of criteria. The aim of this paper is to propose a set of criteria to guide the development, assessment and selection of candidate bolt-on descriptors.

methodsCriteria were developed using an iterative approach. First, existing criteria were identified from the literature including those used to guide the development of MAUIs, the COSMIN checklist and reviews of existing bolt-ons. Second, processes used to develop bolt-ons based on qualitative and quantitative approaches were considered. The information from these two stages was formalised into draft development and selection criteria. These were reviewed by the project team and iteratively refined.

resultsOverall, 23 criteria for the development, assessment and selection of candidate bolt-ons were formulated. Development criteria focused on issues relating to i) structure, ii) language, and iii) consistency with the existing EQ-5D dimension structure. Assessment and selection criteria focused on face and content validity and classical psychometric indicators.

conclusionThe criteria generated can be used to guide the development of bolt-ons across different health areas. They can also be used to assess existing bolt-ons, and inform their inclusion in studies and patient groups where the EQ-5D may lack content validity.

Indexed as

Health StatusQuality of LifeHumansPsychometricsReproducibility of ResultsSurveys and QuestionnairesBolt-onsEQ-5DHealth-related quality of lifePsychometrics

Identifiers

PMID35486216
PMCPMC9470642

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.