Evidence map›Paper›PMID 35486177›Full record

ArticleWorld journal of urology2022

Treatment trends for muscle-invasive bladder cancer in Germany from 2006 to 2019.

Luka Flegar, K Kraywinkel, A Zacharis, C Aksoy, R Koch, N Eisenmenger, C Groeben, J Huber

Abstract read
In one paragraph

Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
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  5. A population-based analysis of patterns of care in patients with de novo muscle-invasive bladder cancer from Alberta, Canada.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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  12. Article
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  14. Review
  15. Article
  16. Article
  17. Article
  18. [Prehabilitation prior to radical cystectomy].Urologie (Heidelberg, Germany) · 2023
    Article
  19. Article
  20. Adoption of Lutetium-European journal of nuclear medicine and molecular imaging · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luka FlegarDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany. luka.flegar@uk-gm.de.ORCID http://orcid.org/0000-0002-1477-9161
K KraywinkelNational Center for Cancer Registry Data, Robert Koch Institute, Berlin, Germany.
A ZacharisDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
C AksoyDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
R KochDepartment of Medical Statistics and Biometry, TU Dresden, Dresden, Germany.
N EisenmengerReimbursement Institute RI Innovation GmbH, Hürth, Germany.
C GroebenDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
J HuberDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine national treatment trends of muscle-invasive bladder cancer (MIBC) in Germany with a special focus on radical cystectomy (RC). PATIENTS AND

methodsPopulation-based data were derived from the nationwide hospital billing database of the German Federal Statistical Office and institution-related information from the reimbursement.INFO tool based on hospitals' quality reports from 2006 to 2019. Additionally, we used the German National Center for Cancer Registry data to analyze all cases of bladder cancer with stage ≥ T2 who received RC, chemotherapy, radiation therapy or a combination from 2006 to 2017.

resultsThe annual number of RC cases in Germany increased by 28% from 5627 cases in 2006 to 7292 cases in 2019 (p = 0.001). The proportion of patients undergoing RC remained constant at about 75% in all age groups between 2006 and 2017 (p = 0.3). Relative to all performed RC, the proportion of patients > 75 years increased from 25% in 2006 to 38% in 2019 (p = 0.03). The proportion of patients receiving a combination of RC and chemotherapy increased from 9% in 2006 to 13% in 2017 (p = 0.005). In 2006, 8 of 299 urology departments (2.7%) performed more than 50 RCs per year, which increased to 17 of 360 (4.7%) in 2019. In 2019, 107 departments (29%) performed 25-49 RCs and 236 (66%) departments performed < 25 RCs.

conclusionIn Germany, three out of four patients with MIBC receive RC and the proportion of patients > 75 years is increasing. The combination of surgery and chemotherapy is increasingly used. With overall increasing case numbers, there is a slight tendency towards centralization.

Indexed as

Urinary Bladder NeoplasmsCystectomyGermanyHumansMusclesNeoadjuvant TherapyNeoplasm InvasivenessUrinary BladderCentralizationHealth services researchMuscle-invasive bladder cancerPopulation-based analysisRadical cystectomy

Identifiers

PMID35486177
PMCPMC9237006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.