Evidence map›Paper›PMID 35486145›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Lymphopenia in patients affected by SARS-CoV-2 infection is caused by margination of lymphocytes in large bowel: an [

Alberto Signore, Chiara Lauri, Marzia Colandrea, Marco Di Girolamo, Erika Chiodo, Chiara Maria Grana, Giuseppe Campagna, Antonio Aceti

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alberto SignoreNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy. alberto.signore@uniroma1.it.ORCID 0000-0001-8923-648X
Chiara LauriNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-0314-5059
Marzia ColandreaNuclear Medicine Division, European Institute of Oncology - IRCCS, Milan, Italy.ORCID 0000-0001-6684-2938
Marco Di GirolamoRadiology Unit, AOU Sant'Andrea, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-8887-2281
Erika ChiodoNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-8899-338X
Chiara Maria GranaNuclear Medicine Division, European Institute of Oncology - IRCCS, Milan, Italy.ORCID 0000-0002-3808-2174
Giuseppe CampagnaNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-1884-9171
Antonio AcetiInfection Unit, Department NESMOS, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-5707-4620
Sapienza University of Rome · ITEuropean Institute of Oncology · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the cause of lymphopenia in patients with newly diagnosed COVID-19, we measured [

methodsWe studied, by [

resultsPatients had moderate severity COVID-19 syndrome. Basal [

conclusionsThese findings indicate that lymphopenia in COVID-19 patients is associated with large bowel inflammation supporting the hypothesis that CD4 + lymphocytes migrate to peripheral lymphoid tissues in the bowel.

Indexed as

COVID-19LymphopeniaFluorodeoxyglucose F18HumansLymphocytesPositron Emission Tomography Computed TomographyRadiopharmaceuticalsSARS-CoV-2Tomography, X-Ray ComputedFluorodeoxyglucose F18Radiopharmaceuticals[18F]FDG PET/CTCOVID-19LymphopeniaPneumoniaSARS-CoV-2

Identifiers

PMID35486145
PMCPMC9050483
OpenAlexW4225094282

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.