Evidence map›Paper›PMID 35486028›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Sarcopenic visceral obesity is associated with increased post-liver transplant mortality in acutely ill patients with cirrhosis.

Nghiem B Ha, Aldo J Montano-Loza, Elizabeth J Carey, Shezhang Lin, Amy M Shui, Chiung-Yu Huang, Michael A Dunn, Jennifer C Lai

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Use of Cross-Sectional Imaging Body Composition Assessment to Predict Pancreas Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nghiem B HaDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, California, USA.ORCID 0000-0002-1980-1807
Aldo J Montano-LozaDivision of Gastroenterology and Liver Unit, Department of Medicine, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0002-2511-7980
Elizabeth J CareyDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.ORCID 0000-0001-8580-2122
Shezhang Lin3D Lab, Center for Intelligent Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.ORCID 0000-0002-5128-7510
Amy M ShuiBiostatistics Core, Department of Surgery, University of California, San Francisco, California, USA.ORCID 0000-0002-8243-6910
Chiung-Yu HuangBiostatistics Core, Department of Surgery, University of California, San Francisco, California, USA.ORCID 0000-0003-2313-3562
Michael A DunnDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, and Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-0954-0498
Jennifer C LaiDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, California, USA.ORCID 0000-0003-2092-6380

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationR01AG059183 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer C. Lai · 2018 to 2026
$9.9M
NRSA Hepatology Training GrantT32DK060414 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mandana Khalili, JACQUELYN J. MAHER · 2002 to 2026
$6.8M
Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantationR21AG067554 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAI, JENNIFER C. · 2020 to 2021
$444k
NIA NIH HHS R01 AG059183NIA NIH HHS R21 AG067554NIDDK NIH HHS P30 DK026743NIDDK NIH HHS T32 DK060414
6 · The paper itself

Abstract

"Sarcopenic obesity" refers to a condition of low muscle mass in the context of obesity, though may be difficult to assess in patients with cirrhosis who are acutely ill. We aimed to define sarcopenic visceral obesity (SVO) using CT-based skeletal muscle index (SMI) and visceral-to-subcutaneous adipose tissue ratio (VSR) to examine its association with post-transplant mortality. We analyzed 116 adult inpatients with cirrhosis who were urgently listed and transplanted between 1/2005 and 12/2017 at 4 North American transplant centers. SVO was defined as patients with sarcopenia (SMI <50 cm

Indexed as

Liver NeoplasmsLiver TransplantationSarcopeniaAdultFemaleHumansLiver CirrhosisMaleMuscle, SkeletalObesityObesity, AbdominalRetrospective StudiesRisk Factorsbody compositionskeletal muscle masssubcutaneous adipose tissuevisceral adipose tissuevisceral-to-subcutaneous adipose tissue ratio

Identifiers

PMID35486028
PMCPMC9427718

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.