Evidence map›Paper›PMID 35485596›Full record

ArticleNMR in biomedicine2022

Synthetic MRI improves radiomics-based glioblastoma survival prediction.

Elisa Moya-Sáez, Rafael Navarro-González, Santiago Cepeda, Ángel Pérez-Núñez, Rodrigo de Luis-García, Santiago Aja-Fernández, Carlos Alberola-López

Abstract read
In one paragraph

Article in NMR in biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisa Moya-SáezLaboratorio de Procesado de Imagen, Universidad de Valladolid, Valladolid.ORCID 0000-0003-4945-3193
Rafael Navarro-GonzálezLaboratorio de Procesado de Imagen, Universidad de Valladolid, Valladolid.ORCID 0000-0002-2900-4107
Santiago CepedaDepartamento de Neurocirugía, Hospital Universitario Río Hortega, Valladolid, Spain.ORCID 0000-0003-1667-8548
Ángel Pérez-NúñezDepartamento de Neurocirugía, Hospital Universitario 12 de Octubre, Madrid, Spain.ORCID 0000-0002-2391-6586
Rodrigo de Luis-GarcíaLaboratorio de Procesado de Imagen, Universidad de Valladolid, Valladolid.ORCID 0000-0001-5023-6490
Santiago Aja-FernándezLaboratorio de Procesado de Imagen, Universidad de Valladolid, Valladolid.ORCID 0000-0002-5337-5071
Carlos Alberola-LópezLaboratorio de Procesado de Imagen, Universidad de Valladolid, Valladolid.ORCID 0000-0003-3684-0055

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma is an aggressive and fast-growing brain tumor with poor prognosis. Predicting the expected survival of patients with glioblastoma is a key task for efficient treatment and surgery planning. Survival predictions could be enhanced by means of a radiomic system. However, these systems demand high numbers of multicontrast images, the acquisitions of which are time consuming, giving rise to patient discomfort and low healthcare system efficiency. Synthetic MRI could favor deployment of radiomic systems in the clinic by allowing practitioners not only to reduce acquisition time, but also to retrospectively complete databases or to replace artifacted images. In this work we analyze the replacement of an actually acquired MR weighted image by a synthesized version to predict survival of glioblastoma patients with a radiomic system. Each synthesized version was realistically generated from two acquired images with a deep learning synthetic MRI approach based on a convolutional neural network. Specifically, two weighted images were considered for the replacement one at a time, a T2w and a FLAIR, which were synthesized from the pairs T1w and FLAIR, and T1w and T2w, respectively. Furthermore, a radiomic system for survival prediction, which can classify patients into two groups (survival >480 days and

Indexed as

Brain NeoplasmsGlioblastomaHumansMagnetic Resonance ImagingRetrospective Studiesglioblastomaradiomicssurvival predictionsynthetic MRI

Identifiers

PMID35485596
PMCPMC9542221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.