Evidence map›Paper›PMID 35485569›Full record

ArticleUlusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES2022

Predictive value of serum sodium level in determining perforated appendicitis.

Veysel Barış Turhan, Abdulkadir Ünsal, Bülent Öztürk, Doğan Öztürk, Hakan Buluş

Open access · hybridAbstract read
In one paragraph

Article in Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Biomarkers in medicine · 2025
    Article
  5. Observational
  6. Article
  7. Article
  8. A new, simple marker for predicting complicated appendicitis in patients with normal white blood cell count indicator; LUC.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Veysel Barış TurhanDepartment of General Surgery, University of Health Sciences, Keçiören Training and Research Hospital, Ankara-Turkey.
Abdulkadir ÜnsalDepartment of General Surgery, University of Health Sciences, Keçiören Training and Research Hospital, Ankara-Turkey.
Bülent ÖztürkDepartment of General Surgery, University of Health Sciences, Keçiören Training and Research Hospital, Ankara-Turkey.
Doğan ÖztürkDepartment of General Surgery, University of Health Sciences, Keçiören Training and Research Hospital, Ankara-Turkey.
Hakan BuluşDepartment of General Surgery, University of Health Sciences, Keçiören Training and Research Hospital, Ankara-Turkey.
Sağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to investigate the predictive value of hyponatremia as a new biochemical marker for the early and accurate preoperative diagnosis of complicated appendicitis in the adult population.

methods732 patients who were operated for acute appendicitis (AA) and diagnosed as perforation intraoperatively were evaluated retrospectively. Serum sodium, C-reactive protein (CRP), and leukocyte levels of patients with perforated and nonperforated appendicitis were compared.

resultsPerforated appendicitis patients had statistically lower serum Na values (p<0.001). Similarly, patients without perforated appendicitis had higher serum CRP values (p<0.001). In patients diagnosed with perforated AA, the sensitivity of plasma sodium concentration was 63%, and the specificity was 66%. The threshold value of plasma sodium concentration ≤137.5 mEq/L had the best possible sensitivity and specificity.

conclusionHyponatremia is a new marker of perforated appendicitis and therefore, serum sodium level measurement should be considered in patients with a clinical presentation consistent with appendicitis if complications are suspected.

Indexed as

AppendicitisHyponatremiaAdultBiomarkersC-Reactive ProteinHumansRetrospective StudiesSensitivity and SpecificitySodiumBiomarkersC-Reactive ProteinSodium

Identifiers

PMID35485569
PMCPMC10493525
OpenAlexW4214565039

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.