Evidence map›Paper›PMID 35485368›Full record

ArticleGut microbes

Disordered development of gut microbiome interferes with the establishment of the gut ecosystem during early childhood with atopic dermatitis.

Min-Jung Lee, Yoon Mee Park, Byunghyun Kim, In Hwan Tae, Nam-Eun Kim, Marina Pranata, Taewon Kim, Sungho Won, Nam Joo Kang, Yun Kyung Lee and 4 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

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  12. Skin-lung axis in the atopic march: The immune link from skin to lungs.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  13. ButyrylatedActa pharmaceutica Sinica. B · 2025
    Article
  14. Strain-Level Differences ofJournal of microbiology and biotechnology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Min-Jung LeeDepartment of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, Republic of Korea.
Yoon Mee ParkAsan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.ORCID 0000-0003-4760-9262
Byunghyun KimSeoul Center, Korea Basic Science Institute, Seoul, Republic of Korea.
In Hwan TaeSeoul Center, Korea Basic Science Institute, Seoul, Republic of Korea.
Nam-Eun KimDepartment of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0003-4155-2584
Marina PranataDepartment of Integrated Biomedical Science, Soonchunhyang Institute of Medi-Bioscience, Soonchunhyang University, Cheonan, Republic of Korea.
Taewon KimSchool of Food Science and Biotechnology, Kyungpook National University, Daegu, Republic of Korea.
Sungho WonDepartment of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0001-5751-5089
Nam Joo KangSchool of Food Science and Biotechnology, Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0003-1500-2845
Yun Kyung LeeDepartment of Integrated Biomedical Science, Soonchunhyang Institute of Medi-Bioscience, Soonchunhyang University, Cheonan, Republic of Korea.
Dong-Woo LeeDepartment of Biotechnology, Yonsei University, Seoul, Republic of Korea.ORCID 0000-0002-2272-8321
Myung Hee NamSeoul Center, Korea Basic Science Institute, Seoul, Republic of Korea.
Soo-Jong HongDepartment of Pediatrics, Childhood Asthma Atopy Center, Humidifier Disinfectant Health Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-1409-2113
Bong-Soo KimDepartment of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, Republic of Korea.ORCID 0000-0003-1243-8280
Hallym University · KRKorea Basic Science Institute · KRKyungpook National University · KRSeoul National University · KRSoonchunhyang University · KRAsan Medical Center · KRUlsan College · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome influences the development of allergic diseases during early childhood. However, there is a lack of comprehensive understanding of microbiome-host crosstalk. Here, we analyzed the influence of gut microbiome dynamics in early childhood on atopic dermatitis (AD) and the potential interactions between host and microbiome that control this homeostasis. We analyzed the gut microbiome in 346 fecal samples (6-36 months; 112 non-AD, 110 mild AD, and 124 moderate to severe AD) from the Longitudinal Cohort for Childhood Origin of Asthma and Allergic Disease birth cohort. The microbiome-host interactions were analyzed in animal and

Indexed as

Dermatitis, AtopicGastrointestinal MicrobiomeMicrobiotaAnimalsButyratesFatty Acids, VolatileHumansMiceButyratesFatty Acids, Volatileatopic dermatitisdevelopmentGuthomeostasismicrobiome

Identifiers

PMID35485368
PMCPMC9067516
OpenAlexW4225124967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.