Evidence map›Paper›PMID 35485284›Full record

ArticleMolecular medicine reports2022

TXNDC9 knockdown inhibits lung adenocarcinoma progression by targeting YWHAG.

Jing Wang, Xiaotao Pan, Jie Li, Jin Zhao

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jing WangRespiratory and Critical Care Medicine Department, The Second People's Hospital of Shaanxi Province, Xi'an, Shaanxi 710005, P.R. China.
Xiaotao PanGeneral Surgery Department, Shaanxi Provincial Cancer Hospital, Xi'an, Shaanxi 710600, P.R. China.
Jie LiRadiotherapy Department, Shaanxi Provincial Cancer Hospital, Xi'an, Shaanxi 710600, P.R. China.
Jin ZhaoRadiotherapy Department, Shaanxi Provincial Cancer Hospital, Xi'an, Shaanxi 710600, P.R. China.
Shaanxi Provincial People's Hospital · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung adenocarcinoma (LUAD) is the most common form of lung cancer and with the highest mortality rate. Therefore, the identification and development of effective methods for the treatment of LUAD is of great importance. The present study aimed to investigate the role of thioredoxin domain‑containing protein 9 (TXNDC9) and tyrosine 3‑monooxygenase/tryptophan 5‑monooxygenase activation protein γ (YWHAG; also known as 14‑3‑3γ) in the progression of LUAD. The expression of TXNDC9 and its association with the survival of patients with LUAD was analyzed using Encyclopedia of RNA Interactomes. Reverse transcription‑quantitative PCR and western blot analysis were used to detect TXNDC9 mRNA and protein expression levels, respectively, in

Indexed as

AdenocarcinomaAdenocarcinoma of LungLung Neoplasms14-3-3 ProteinsCell Line, TumorCell ProliferationHumansThioredoxins14-3-3 ProteinsThioredoxinsTXNDC9 protein, humanYWHAG protein, human14‑3‑3γlung adenocarcinomathioredoxin domain‑containing protein 9tyrosine 3‑monooxygenase/tryptophan 5‑monooxygenase activation protein γ

Identifiers

PMID35485284
PMCPMC9073845
OpenAlexW4225116285

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.