Evidence map›Paper›PMID 35485194›Full record

ArticleThe Journal of experimental biology2022

Fast stretching of skeletal muscle fibres abolishes residual force enhancement.

Shuyue Liu, Venus Joumaa, Walter Herzog

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of experimental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shuyue LiuHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada, T2N 1N4.ORCID 0000-0001-9890-8049
Venus JoumaaHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada, T2N 1N4.
Walter HerzogHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada, T2N 1N4.
University of Calgary · CA

Funding

Collaborative Research: A Predictive Theory of Muscle Energy Consumption R01GM135923 · NIGMS · WORCESTER POLYTECHNIC INSTITUTE · PI WALCOTT, SAMUEL · 2019 to 2022
$1.5M
Canada Research ChairsKillam TrustsNatural Sciences and Engineering Research Council of CanadaNIGMS NIH HHS R01 GM135923NIH HHS
6 · The paper itself

Abstract

The steady-state isometric force of a muscle after active stretching is greater than the steady-state force for a purely isometric contraction at the same length and activation level. The mechanisms underlying this property, termed residual force enhancement (rFE), remain unknown. When myofibrils are actively stretched while cross-bridge cycling is inhibited, rFE is substantially reduced, suggesting that cross-bridge cycling is essential to produce rFE. Our purpose was to further investigate the role of cross-bridge cycling in rFE by investigating whether fast stretching that causes cross-bridge slipping is associated with a loss of rFE. Skinned fibre bundles from rabbit psoas muscles were stretched slowly (0.08 µm s-1) or rapidly (800 µm s-1) while activated, from an average sarcomere length of 2.4 to 3.2 µm. Force was enhanced by 38±4% (mean±s.e.m) after the slow stretches but was not enhanced after the fast stretches, suggesting that proper cross-bridge cycling is required to produce rFE.

Indexed as

Isometric ContractionMuscle Fibers, SkeletalAnimalsBicyclingMechanical PhenomenaMuscle ContractionMuscle, SkeletalRabbitsSarcomeresCross-bridge cyclingFast stretchMuscle slippingSlow stretchThree filament sarcomere modelTitin

Identifiers

PMID35485194
PMCPMC9206448
OpenAlexW4225123023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.