Evidence map›Paper›PMID 35484955›Full record

ArticlePediatric blood & cancer2022

Low numbers of COVID-19 in Swedish pediatric oncology patients during the first pandemic year despite an open society.

Emil Sundberg, Kleopatra Georgantzi, Cecilia Langenskiöld, Ladislav Król, Frans Nilsson, Hartmut Vogt, Josefine Palle, Torben Ek, Anna Nilsson

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Pediatric blood & cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Emil SundbergDepartment of Children's Oncology and Hematology, Uppsala University Hospital, Uppsala, Sweden.
Kleopatra GeorgantziDivision of Pediatric Hematology-Oncology, Tema Barn, Astrid Lindgren Children's Hospital, Stockholm, Sweden.
Cecilia LangenskiöldChildren's Cancer Centre, Queen Silvia Children's Hospital, Gothenburg, Sweden.
Ladislav KrólDivision of Pediatric Hematology-Oncology, Skåne University Hospital, Lund, Sweden.
Frans NilssonDivision of Pediatric Hematology-Oncology, Umeå University Hospital, Umeå, Sweden.
Hartmut VogtCrown Princess Victoria's Child and Youth Hospital, Division of Pediatric Hematology-Oncology B153, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Josefine PalleDepartment of Children's Oncology and Hematology, Uppsala University Hospital, Uppsala, Sweden.
Torben EkChildren's Cancer Centre, Queen Silvia Children's Hospital, Gothenburg, Sweden.
Anna NilssonDivision of Pediatric Hematology-Oncology, Tema Barn, Astrid Lindgren Children's Hospital, Stockholm, Sweden.ORCID 0000-0001-5885-7101
Drottning Silvias barn- och ungdomssjukhus · SEKarolinska Institutet · SELinköping University · SESachs' Children and Youth Hospital · SESkåne University Hospital · SEUmeå University · SEUppsala University · SEUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSweden adopted a different strategy than many other countries to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and kept most schools open. Initial reports from China suggested that coronavirus disease 2019 (COVID-19) was milder in children compared to adults, but there was a lack of data from immunocompromised children. Therefore, we investigated the rate of verified SARS-CoV-2 infections in our Swedish pediatric oncology patients. PROCEDURE: This was a multicenter retrospective study. A questionnaire including patient data as well as SARS-CoV-2 data was sent to the six Swedish childhood cancer centers in May 2021.

resultsDuring the first pandemic year, 49 patients were identified as SARS-CoV-2 positive, and 22 (45%) children were hospitalized with COVID-19. Two children needed intensive care, but no COVID-19-related deaths were reported. Most patients (n = 36, 73%) were on active chemotherapy treatment and 23 children (49%) attended school or daycare at least part-time. Half of the SARS-CoV-2-positive patients experienced a delay in cancer treatment.

conclusionsDespite the rapid spread of SARS-CoV-2 in Sweden, without a strict lockdown of the society, the number of nationally reported pediatric oncology patients with polymerase chain reaction (PCR)-verified infection was low, and the majority of children had mild disease. Our data show that treatment interruptions occurred frequently and this should clearly be avoided for the coming years.

Indexed as

COVID-19NeoplasmsAdultChildCommunicable Disease ControlHumansPandemicsRetrospective StudiesSARS-CoV-2SwedenCOVID-19hematologyoncologypediatricsSARS-CoV-2

Identifiers

PMID35484955
PMCPMC9088657
OpenAlexW4225134861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.