Evidence map›Paper›PMID 35484785›Full record

ArticleHelicobacter2022

Prevalence of Helicobacter pylori infection among resettled refugees presenting to a family medicine clinic in the United States.

Nadia Saif, Nicole Jensen, Elizabeth Farrar, Sarah Blackstone, Fern R Hauck

Open access · hybridAbstract read
In one paragraph

Article in Helicobacter, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nadia SaifUniversity of Maryland School of Medicine, University of Maryland at Baltimore, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-5024-0676
Nicole JensenDepartment of Family Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Elizabeth FarrarDepartment of Family Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Sarah BlackstoneDepartment of Family Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Fern R HauckDepartment of Family Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.ORCID https://orcid.org/0000-0001-7309-7665
University of Virginia Health System · USUniversity of Maryland, Baltimore · US

Funding

University of Virginia
6 · The paper itself

Abstract

backgroundAlthough endemic to much of the global population, few studies have examined Helicobacter pylori (H. pylori) in US refugee populations. This study investigates the prevalence of H. pylori infection and barriers to treatment in the International Family Medicine Clinic (IFMC), a primary care refugee clinic, in central Virginia. MATERIALS AND

methodsWe conducted a chart review of 188 refugee patients of the IFMC who were referred for an H. pylori test between January 1, 2019, and December 31, 2020. Recorded measures included patient demographics, H. pylori test result, treatment of initial infection, completion of test of cure (TOC), TOC results, salvage therapy, and barriers to treatment. Binary logistic regression was performed to examine the association between demographic factors and H. pylori test results.

resultsOf the 171 patients who completed an H. pylori test, 94 tested positive (54.9%). Of the 93 patients that were subsequently treated, 76 were treated with clarithromycin triple therapy (82%). Forty-eight patients (52%) completed a TOC after completing treatment, and 21 (43%) of these patients remained positive, indicating persistent infection. Eighteen patients (90%) who remained positive for H. pylori were subsequently treated with quadruple therapy. Patients under 18 (OR = 0.25, p < 0.01) and patients with a history of previous H. pylori (OR = 0.44, p < 0.05) were less likely to have positive results on initial H. pylori testing. Common barriers to treatment included pregnancy, religious observance (e.g., fasting), and health system complications (e.g., prior authorization for medications, cost of treatment).

conclusionsThe prevalence of H. pylori among refugees at the IFMC was higher than the overall prevalence estimate for the United States, which is consistent with previous studies. This work represents an updated picture of H. pylori prevalence among refugees in the United States and contributes to the identification of treatment barriers.

Indexed as

Helicobacter InfectionsHelicobacter pyloriRefugeesAmoxicillinAnti-Bacterial AgentsClarithromycinDrug Therapy, CombinationFamily PracticeHumansPrevalenceUnited StatesAmoxicillinAnti-Bacterial AgentsClarithromycinantibiotic therapyepidemiologyhelicobacter pylori infectionprevalencerefugeestreatment failure

Identifiers

PMID35484785
PMCPMC9286549
OpenAlexW4225101412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.