Evidence map›Paper›PMID 35484470›Full record

ArticleGeroScience2022

Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project.

Emily E Bray, Zihan Zheng, M Katherine Tolbert, Brianah M McCoy, Dog Aging Project Consortium, Matt Kaeberlein, Kathleen F Kerr

Open access · greenAbstract read
In one paragraph

Article in GeroScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Emily E BrayArizona Canine Cognition Center, School of Anthropology, University of Arizona, Tucson, AZ, USA. ebray@email.arizona.edu.
Zihan ZhengDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
M Katherine TolbertGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA.
Brianah M McCoySchool of Life Sciences, Arizona State University, Tempe, AZ, USA.
Dog Aging Project Consortium
Matt KaeberleinDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Kathleen F KerrDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Seattle University · USUniversity of Washington · USArizona State University · USTexas A&M University · USUniversity of Arizona · US

Funding

The Dog Aging Project: Genetic and Environmental Determinants of Healthy Aging in Companion Dogs Competitive RevisionU19AG057377 · NIA · UNIVERSITY OF WASHINGTON · PI KEENE, CHRISTOPHER DIRK, PROMISLOW, DANIEL EDWARD · 2018 to 2023
$29.0M
Developing the Privately Owned Companion Dog as a Model for Alzheimers DiseaseR24AG073137 · NIA · UNIVERSITY OF WASHINGTON · PI KEENE, CHRISTOPHER DIRK, MCGRATH, STEPHANIE · 2021 to 2024
$5.1M
NIA NIH HHS R24 AG073137NIA NIH HHS U19 AG057377
6 · The paper itself

Abstract

A variety of diets have been studied for possible anti-aging effects. In particular, studies of intermittent fasting and time-restricted feeding in laboratory rodents have found evidence of beneficial health outcomes. Companion dogs represent a unique opportunity to study diet in a large mammal that shares human environments. The Dog Aging Project has been collecting data on thousands of companion dogs of all different ages, sizes, and breeds since 2019. We leveraged this diverse cross-sectional dataset to investigate associations between feeding frequency and cognitive function (n = 10,474) as well as nine broad categories of health conditions (n = 24,238). Controlling for sex, age, breed, and other potential confounders, we found that dogs fed once daily rather than more frequently had lower mean scores on a cognitive dysfunction scale, and lower odds of having gastrointestinal, dental, orthopedic, kidney/urinary, and liver/pancreas disorders. Therefore, we find that once-daily feeding is associated with better health in multiple domains. Future research with longitudinal data can provide stronger evidence for a possible causal effect of feeding frequency on health in companion dogs.

Indexed as

AgingPetsAnimalsBreedingCognitionCross-Sectional StudiesDogsMammalsCanineCanine cognitive dysfunctionFeeding frequencyHealthy agingTime-restricted feeding

Identifiers

PMID35484470
PMCPMC9213604
OpenAlexW4225128156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.