ArticleScientific reports2022
Toxicity and biochemical impact of methoxyfenozide/spinetoram mixture on susceptible and methoxyfenozide-selected strains of Spodoptera littoralis (Lepidoptera: Noctuidae).
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 22 citations in OpenAlex.
- Impact of Type of Lignin, Alkaline and Lignosulfonate, on Release and Soil Adsorption of Methoxyfenozide Delivered with Lignin-ACS omega · 2026Article
- Transcriptomic Insights into the Synergistic Mechanism of Spinosad-Indoxacarb Mixtures AgainstInsects · 2026Article
- Photo-induced selective N-N bond construction via harnessing nitrene release and transfer.Nature communications · 2026Article
- Pesticide Surveillance in Fruits and Vegetables from Romanian Supply: A Data-Driven Approach.Journal of xenobiotics · 2025Article
- Target Enzymes ofInsects · 2024Article
- Field Efficacy, Sub-lethal, and Biochemical Effects of Certain Biorational Insecticides Against the New Intruder, Spodoptera frugiperda in Bani-Suef, Upper Egypt.Neotropical entomology · 2023Article
- Development of a Nickel-Catalyzed N-N Coupling for the Synthesis of Hydrazides.Journal of the American Chemical Society · 2023Article
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Authors and funding
3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Methoxyfenozide (M) is one of the selective insecticides used in integrated pest management (IPM) programs for lepidopteran pests. However, recent studies reported a development of M-resistance, which prompted us to look for alternatives. Here, we investigate the potency of a mixture of M with spinetoram (Sp) on M-resistant insects. In the laboratory, a selection pressure with M has carried out on Spodoptera littoralis (Lepidoptera: Noctuidae) strains. A dipping technique was used to evaluate the toxicity of a sublethal concentration of M and Sp. on S. littoralis larvae, and the same concentrations were used to assess the toxic impact of their combination on susceptible (SUS) and M-selected (MS) strains. The toxicity of M/Sp mixtures was computed using a combination index equation, and a potentiation effect was observed in the two tested strains. Synergism tests revealed that piperonyl butoxide had considerable synergistic effects on M toxicity in the MS strain. The results revealed that the M/Sp mixture's negative effect on both monooxygenases and esterases is most likely the cause of its potentiation effect on the SUS and MS strains. It was concluded that M/Sp mixtures are effective against M-resistant S. littoralis strains, so these can be used in IPM programs.
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