Evidence map›Paper›PMID 35484377›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2022

Household transmission of COVID-19 according to index case: children, parents, and healthcare workers.

Joseane Mayara Almeida Carvalho, Clarice Neves Camargo, Luciano Kleber de Souza Luna, Anna Clara Rabha, Danielle Dias Conte, Roberta Ferreira Mariano, Francisco Ivanildo de Oliveira Junior, Gabriela Rodrigues Barbosa, Luiz Vinicius Leão Moreira, Ana Paula Cunha Chaves and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Joseane Mayara Almeida CarvalhoLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil. joseanemayara1@gmail.com.ORCID http://orcid.org/0000-0003-1186-8895
Clarice Neves CamargoLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-1710-459X
Luciano Kleber de Souza LunaLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3552-5507
Anna Clara RabhaInstituto de Pesquisa PENSI - Hospital Infantil Sabará, São Paulo, SP, Brazil.
Danielle Dias ConteLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4351-0831
Roberta Ferreira MarianoInstituto de Pesquisa PENSI - Hospital Infantil Sabará, São Paulo, SP, Brazil.
Francisco Ivanildo de Oliveira JuniorInstituto de Pesquisa PENSI - Hospital Infantil Sabará, São Paulo, SP, Brazil.
Gabriela Rodrigues BarbosaLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3386-8581
Luiz Vinicius Leão MoreiraLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-6836-0227
Ana Paula Cunha ChavesLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-0321-6977
Ana Helena PerosaLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.
Nancy BelleiLaboratory of Clinical Virology, Infectious Diseases Divison, Departament of Medicine, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6080-5693
Universidade Federal de São Paulo · BRHospital Infantil Albert Sabin · BRAssociação Paulista de Medicina · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 01Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/11719-0
6 · The paper itself

Abstract

The first SARS-CoV-2 intrafamilial transmission was investigated in China. We evaluated the dynamics of SARS-CoV-2 transmission in 242 individuals from 60 family clusters, including 30 healthcare workers (HCW) and 30 patients, in São Paulo city. Sixty index cases with COVID-19 were selected, being 30 HCW index cases from Hospital São Paulo (HSP) and its 93 household contacts and 30 index case patients from Hospital Infantil Sabará (HIS) and its 89 household contacts. Asymptomatic and symptomatic individuals participating were tested for COVID-19. The secondary attack rates in the family clusters of HCW and HIS patients were 37.63% and 68.54%, respectively. Considering all households, the transmission from adults to children was 55.4%, while the transmission from children to children was 37.5%. Children were more infected if the index case was an adult, suggesting that children were less competent to transmit. The average time for a household to be COVID-19 positive was 4 and 3 days for HCW and HIS patients. Although HCW have a higher risk of infection and social vulnerability, the secondary attack rate was lower than that observed for HIS patients, possibly because HCW are more aware of transmission risks than the general community.

Indexed as

COVID-19AdultBrazilChildHealth PersonnelHumansParentsSARS-CoV-2ChildrenCOVID-19Healthcare workersHousehold transmissionSARS-CoV-2

Identifiers

PMID35484377
PMCPMC9049928
OpenAlexW4225099271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.