Trial reportScientific reports2022
A randomised study to assess the nicotine pharmacokinetics of an oral nicotine pouch and two nicotine replacement therapy products.
Trial report in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 47 citations in OpenAlex.
- Switching from Cigarettes to E-Cigarettes and Oral Nicotine Pouches in Adults with Low-Income Who Smoke: Qualitative Findings from a Pilot Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Trial
- Evaluation of high-nicotine oral products shows potential to reduce tobacco-related harm by offering satisfying alternatives.Scientific reports · 2025Trial
- Characterization of the nicotine uptake and safety of Nordic spirit tobacco-free oral nicotine pouches: A randomized cross-over study.Psychopharmacology · 2025Trial
- Pilot randomized controlled trial evaluating the effect of random nicotine delivery on cigarettes per day and smoke exposure.Brain research bulletin · 2022Trial
- Velo (BAT) buffet of oral nicotine pouches in Pakistan: varying brand variant levels of nicotine, menthol and other flavour chemicals.Tobacco control · 2026Article
- Development of a model to predict nicotine pharmacokinetics from oral nicotine pouches.Scientific reports · 2026Article
- Switching to alternative tobacco products during unsuccessful smoking quit attempts is not linked to improved quit intention or interest.Addiction science & clinical practice · 2026Article
- Article
- Nicotine pouches: an aid in smoking cessation, or a new public health hazard?Internal and emergency medicine · 2026Review
- Oral nicotine pouches have arrived at U.S. college campuses.Journal of American college health : J of ACH · 2026Article
- Metabolic and nutritional stress-associated dilated cardiomyopathy in the setting of semaglutide use and long-term nicotine replacement therapy: a case report and literature review.Therapeutic advances in drug safety · 2026Article
- Nicotine pouches, oral cancer and tobacco harm reduction: current evidence and research priorities.Frontiers in oral health · 2026Review
- Research on the safety risk of oral nicotine products and its prospects.Current research in toxicology · 2026Review
- Nicotine delivery from and user reactions to nicotine pouches compared to cigarettes.Psychopharmacology · 2025Article
- Physiologically Based Pharmacokinetic Modeling to Predict Nicotine Pharmacokinetics of Nicotine Pouches Under Naturalistic Use Conditions.Journal of clinical pharmacology · 2025Article
- Physiological and subjective effects of an oral nicotine pouch in people who use smokeless tobacco.Experimental and clinical psychopharmacology · 2025Article
- Prevalence, safety, and role of nicotine pouches in smoking cessation among smokers and the public in Saudi Arabia.Scientific reports · 2025Article
- Effects of oral nicotine pouches on cigarette smoking behaviour and tobacco harm exposure: a randomised pilot trial in adults.Tobacco control · 2025Article
- A comprehensive review on oral nicotine pouches: Available scientific evidence and future research needs.Experimental and clinical psychopharmacology · 2025Review
- The Potential Impact of Oral Nicotine Pouches on Public Health: A Scoping Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nicotine replacement therapies (NRTs) are intended for short-term use to help cigarette smokers to quit. Some smokers find NRTs ineffective or seek a more satisfactory source of nicotine. Tobacco-free oral nicotine pouch (NP) products have emerged as a potential reduced risk product compared with cigarettes and other tobacco products. In a randomised crossover clinical study, thirty-four healthy adult smokers were enrolled and their nicotine C
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.