ArticleScientific reports2022
Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 56 citations in OpenAlex.
- Sudden cardiac arrest in young adults: A comprehensive systematic review of epidemiology, aetiology and preventive strategies.Heart international · 2026Review
- Article
- Risk stratification for future cardiac arrest after COVID-19 vaccination.World journal of cardiology · 2025Review
- Cardiovascular events following coronavirus disease 2019 vaccination in adults: a nationwide Swedish study.European heart journal · 2025Article
- Cardiac Arrhythmias and Autonomic Dysfunction Associated With COVID-19: A Scientific Statement From the American Heart Association.Circulation · 2024Review
- Article
- A narrative review of coronavirus (COVID-19) vaccination and its implication in the development of coronary artery disease: an Indian perspective.Indian journal of thoracic and cardiovascular surgery · 2024Article
- Pfizer COVID19 vaccine is not associated with acute cardiovascular events excluding myocarditis- a national self-controlled case series study.Israel journal of health policy research · 2024Article
- Assessment of Risk for Sudden Cardiac Death Among Adolescents and Young Adults After Receipt of COVID-19 Vaccine - Oregon, June 2021-December 2022.MMWR. Morbidity and mortality weekly report · 2024Article
- Serious Safety Signals and Prediction Features Following COVID-19 mRNA Vaccines Using the Vaccine Adverse Event Reporting System.Pharmaceuticals (Basel, Switzerland) · 2024Article
- A young woman with acute coronary syndrome and antiphospholipid syndrome. Is it the antiphospholipid syndrome or COVID-19 vaccination or classical risk as the risk factor? a case report.Journal of medical case reports · 2024Article
- Rate and Cause of Sudden Cardiac Death in the Young During the COVID-19 Pandemic and Vaccination.Circulation · 2023Article
- Risk of cardiac arrhythmia and cardiac arrest after primary and booster COVID-19 vaccination in England: A self-controlled case series analysis.Vaccine: X · 2023Article
- COVAX - Time to reconsider the strategy and its target.Health policy OPEN · 2023Article
- COVID-19 Vaccination and Cardiac Arrhythmias: A Review.Current cardiology reports · 2023Review
- Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned?International journal of molecular sciences · 2023Review
- Benefits and Harms of COVID-19 Vaccines in Cardiovascular Disease: A Comprehensive Review.Journal of lipid and atherosclerosis · 2023Review
- Article
- Review
- Review
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Cardiovascular adverse conditions are caused by coronavirus disease 2019 (COVID-19) infections and reported as side-effects of the COVID-19 vaccines. Enriching current vaccine safety surveillance systems with additional data sources may improve the understanding of COVID-19 vaccine safety. Using a unique dataset from Israel National Emergency Medical Services (EMS) from 2019 to 2021, the study aims to evaluate the association between the volume of cardiac arrest and acute coronary syndrome EMS calls in the 16-39-year-old population with potential factors including COVID-19 infection and vaccination rates. An increase of over 25% was detected in both call types during January-May 2021, compared with the years 2019-2020. Using Negative Binomial regression models, the weekly emergency call counts were significantly associated with the rates of 1st and 2nd vaccine doses administered to this age group but were not with COVID-19 infection rates. While not establishing causal relationships, the findings raise concerns regarding vaccine-induced undetected severe cardiovascular side-effects and underscore the already established causal relationship between vaccines and myocarditis, a frequent cause of unexpected cardiac arrest in young individuals. Surveillance of potential vaccine side-effects and COVID-19 outcomes should incorporate EMS and other health data to identify public health trends (e.g., increased in EMS calls), and promptly investigate potential underlying causes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.