SynthesisNature human behaviour2022
A meta-analysis on the affect regulation function of real-time self-injurious thoughts and behaviours.
Synthesis in Nature human behaviour, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Relationship Between Anger and Nonsuicidal Self-Injury: A Meta-Analysis.Suicide & life-threatening behavior · 2026Pooled it
- The daily association between affect and alcohol use: A meta-analysis of individual participant data.Psychological bulletinPooled it
- High-Intensity Transcranial Alternating Current Stimulation for Emotion Regulation and Attentional Bias in Adolescents With Nonsuicidal Self-Injury: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Nonsuicidal Self-Injury (NSSI) in Virtual Reality: Effect of Blood-Viewing on Affect Controlling for Pain.Journal of clinical psychology · 2026Trial
- Intermittent theta burst stimulation for non-suicidal self-injury in adolescents with major depressive disorder: a randomized, sham-controlled trial.Molecular psychiatry · 2026Trial
- Early remission of deliberate self-harm predicts emotion regulation capacity in adulthood: 12.4 years follow-up of a randomized controlled trial of adolescents with repeated self-harm and borderline features.European child & adolescent psychiatry · 2025Trial
- Sampling methodology and observed data patterns in ecological momentary assessment: A study of nonsuicidal self-injury among high-risk young adults.Psychological assessment · 2026Article
- The Impact of Emotional Arousal on Physical Pain and Numbness in Individuals Who Engage in Non-Suicidal Self-Injury.Suicide & life-threatening behavior · 2026Article
- A real-time exploration of the affect regulation hypothesis surrounding substance use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Development of a Repeat Suicide Risk Management Protocol for Emergency Department Patients With Suicide Attempts: An Exploratory Sequential Mixed-Methods Study.International journal of mental health nursing · 2026Article
- Testing the robustness of daily associations of affect with alcohol and cannabis use.Journal of psychopathology and clinical science · 2026Article
- Integrating Dimensional Personality and Autistic Traits to Predict Suicidal Ideation, Suicide Attempts, and Nonsuicidal Self-Injury in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026Article
- Emotion Differentiation and Dynamics Predicting Suicide Outcomes in High-Risk Adults.Suicide & life-threatening behavior · 2026Article
- A methodological proof-of-concept of a data-driven, personalized, blended digital health intervention for suicidal thoughts and behaviors: A case series.Internet interventions · 2026Article
- Thinking About Suicide for a Long Time: A Scoping Review of Empirical Studies on Persistent Suicidal Ideation.Suicide & life-threatening behavior · 2025Article
- The descent of agamemnon and the disquietude of job: The death of agency as the spur of suicide.Psychological review · 2025Review
- Non-Suicidal Self-Injury and Depressive Symptoms During Adolescence: Testing Directionality.Journal of youth and adolescence · 2025Article
- Within-day associations between affect and intentions to drink alcohol in adolescents and young adults: A registered report.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
- Nightmares and self-injurious thoughts among clinically acute adolescents: Examining negative affect as a potential mechanism.Journal of affective disorders · 2025Article
- Psychosocial dynamics of suicidality and nonsuicidal self-injury: a digital linguistic perspective.Npj mental health research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Prominent theories suggest that self-injurious thoughts and behaviours are negatively reinforced by decreased negative affect. The present meta-analysis quantifies effects from intensive longitudinal studies measuring negative affect and self-injurious thoughts and behaviours. We obtained data from 38 of the 79 studies (48%, 22 unique datasets) involving N = 1,644 participants (80% female, 75% white). Individual-participant data meta-analyses revealed changes in affect pre/post self-injurious thoughts and behaviours. In antecedent models, results supported increased negative affect before nonsuicidal self-injurious behaviour (k = 14, 95% CI 0.09 to 0.31) and suicidal thoughts (k = 14, 95% CI 0.03 to 0.19). For consequence models, negative affect was reduced following nonsuicidal self-injurious thoughts (k = 6, 95% CI -0.79 to -0.44), nonsuicidal self-injurious behaviours (k = 14, 95% CI -0.73 to -0.19) and suicidal thoughts (k = 13, 95% CI -0.79 to -0.23). Findings, which were not moderated by sampling strategies or sample composition, support the affect regulation function of self-injurious thoughts and behaviours.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.