ArticleScientific reports2022
A nationwide cohort study on the risk of ADHD in children with amblyopia mediated by fine motor skill impairment in East Asia.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Convergent genetic pathways linking neuropsychiatric and ocular disorders in children.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Amblyopia and adult health: a comprehensive analysis of long-term systemic, sensory and mental health comorbidities in a national cohort.The British journal of ophthalmology · 2026Article
- Association between eye disorders and the development of ADHD/ADD: a nationwide retrospective cohort study.Eye (London, England) · 2026Article
- Article
- Recommendations for use and coverage of digital, binocular treatments for amblyopia.Journal of managed care & specialty pharmacy · 2025Article
- Psychometric validation of the SNAP-IV rating scale in amblyopic children at high AD/HD risk: structural validity and measurement invariance.Frontiers in psychiatry · 2025Article
- Patching in Children With Unilateral Congenital Cataract and Child Functioning and Parenting Stress.JAMA ophthalmology · 2024Article
- Why You Should Not Estimate Mediated Effects Using the Difference-in-Coefficients Method When the Outcome is Binary.Multivariate behavioral researchArticle
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This national administrative investigation of Republic of Korea compared the risk of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders(ASD) in preschool amblyopic children and identified factors that possibly mediate this association. After propensity score (PS) matching, 7762 amblyopic children and 31,030 non-amblyopic children were included. Amblyopia was associated with ADHD (aOR:1.687; 95% CI 1.444, 1.970) but not with ASD (aOR: 0.591; 95% CI 0.341, 1.026). Fine motor skill impairment was a mediating factor in association of amblyopia with ADHD, accounting for 4.2% (95% CI 1.7, 8.0). In conclusion, amblyopic children have a greater risk of ADHD, and deficits in fine motor skills mediate this association. We suggest increased attention given to fine motor skill underdevelopment in amblyopic children to prevent the development of ADHD.
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