ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2024
Internalizing Symptoms and Adverse Childhood Experiences Associated With Functional Connectivity in a Middle Childhood Sample.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Understanding adverse childhood experiences within the first decade of the ABCD study: A systematic review.Developmental cognitive neuroscience · 2026Pooled it
- Measuring adversity in the ABCD® Study: systematic review and recommendations for best practices.BMC medical research methodology · 2025Pooled it
- A novel early screening approach for MCI due to AD based on a "maze" hand-interaction kinetic paradigm.Frontiers in neuroscience · 2026Article
- Adverse childhood experiences and post-traumatic stress impacts on brain connectivity and alcohol use in adolescence.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025Article
- Perinatal Maternal Depressive Symptoms and Brain Connectivity Among 9- to 15-Year-Old Offspring.JAMA network open · 2025Article
- Latent Default Mode Network Connectivity Patterns: Associations With Sleep Health and Adolescent Psychopathology.Brain and behavior · 2025Article
- Indicators of resource scarcity differentially moderate the impact of threat exposure on psychopathology in a cross-sectional community sample of youth.Frontiers in child and adolescent psychiatry · 2025Article
- Associations between parental psychopathology and youth functional emotion regulation brain networks.Developmental cognitive neuroscience · 2024Article
- Early Life Adversity Predicts Reduced Hippocampal Volume in the Adolescent Brain Cognitive Development Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024Article
- Article
- Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities.Behavior genetics · 2023Article
- A Cross-Sectional Study: Structural and Related Functional Connectivity Changes in the Brain: Stigmata of Adverse Parenting in Patients with Major Depressive Disorder?Brain sciences · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundResearch has found overlapping associations in adults of resting-state functional connectivity (RSFC) to both internalizing disorders (e.g., depression, anxiety) and a history of traumatic events. The present study aimed to extend this previous research to a younger sample by examining RSFC associations with both internalizing symptoms and adverse childhood experiences (ACEs) in middle childhood.
methodsWe used generalized linear mixed models to examine associations between a priori within- and between-network RSFC with child-reported internalizing symptoms and ACEs using the Adolescent Brain Cognitive Development dataset (N = 10,168, mean age = 9.95 years, SD = 0.627).
resultsWe found that internalizing symptoms and ACEs were associated with both multiple overlapping and unique RSFC network patterns. Both ACEs and internalizing symptoms were associated with a reduced anticorrelation between the default mode network and the dorsal attention network. However, internalizing symptoms were uniquely associated with lower within-network default mode network connectivity, while ACEs were uniquely associated with both lower between-network connectivity of the auditory network and cingulo-opercular network, and higher within-network frontoparietal network connectivity.
conclusionsThe present study points to overlap in the RSFC associations with internalizing symptoms and ACEs, as well as important areas of specificity in RSFC associations. Many of the RSFC associations found have been previously implicated in attentional control functions, including modulation of attention to sensory stimuli. This may have critical importance in understanding internalizing symptoms and outcomes of ACEs.
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