Evidence map›Paper›PMID 35483205›Full record

ArticleEpilepsy & behavior : E&B2022

Quality of life in patients with symptomatic epilepsy due to neurocysticercosis.

Willy R Zapata, Susan Y Yang, Javier A Bustos, Isidro Gonzales, Herbert Saavedra, Carolina Guzman, E Javier Pretell, Hector H Garcia, Cysticercosis Working Group In Peru

Open access · greenAbstract read
In one paragraph

Article in Epilepsy & behavior : E&B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Willy R ZapataDepartamento de Epilepsia, Instituto Nacional de Ciencias Neurológicas, Lima, Peru. Electronic address: rewalz@hotmail.com.
Susan Y YangSchool of Medicine, Trinity College Dublin, Dublin, Ireland; Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Javier A BustosCysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Isidro GonzalesCysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Herbert SaavedraCysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Carolina GuzmanCysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
E Javier PretellHospital Nacional Alberto Sabogal, ESSALUD, Callao, Peru.
Hector H GarciaCysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Cysticercosis Working Group In Peru
Instituto Nacional de Enfermedades Neoplásicas · PEInstituto Nacional de Ciencias NeurológicasUniversidad Peruana Cayetano Heredia · PE

Funding

Training in Parasitic Diseases and Central Nervous System Infections in Peru.D43TW001140 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GARCIA, HECTOR HUGO, GILMAN, ROBERT H · 1999 to 2025
$5.7M
FIC NIH HHS D43 TW001140
6 · The paper itself

Abstract

backgroundNeurocysticercosis (NCC) is a common cause of late-onset epilepsy worldwide, but there is still minimal information regarding its impact on a patient's quality of life. This study evaluated quality of life in a series of patients with epilepsy secondary to NCC using the QOLIE (Quality of Life in Epilepsy)-31 questionnaire. METHODOLOGY: This cross-sectional study included 155 Peruvian patients between 16 and 70 years of age with epilepsy due to viable intraparenchymal NCC, who enrolled in two trials of anti-parasitic treatment during the period 2006-2011. The QOLIE-31 questionnaire was applied before the onset of anti-parasitic treatment. The associations between QOLIE-31 scores, sociodemographic characteristics, clinical, and neuroimaging data were analyzed with Kruskal-Wallis test and generalized linear models (GLM).

resultsThe average QOLIE-31 score was 55.8 (SD ± 7.6), with 119 individuals (76.8%) scoring in the poor quality-of-life category. Generalized tonic-clonic seizures and secondarily generalized epileptic seizures were associated with a lower QOLIE-31, as well as a low level of education with a value of p = 0.05. There were no associations between QOLIE-31 scores and other variables such as sex, age, antiepileptic medication, number of parasitic cysts, and number of compromised brain regions. On multivariate analysis, a greater number of generalized epileptic seizures maintained a statistically significant association with detrimental QOLIE-31 scores.

conclusionQuality of life is affected in NCC, mainly in relation to the number of prior generalized epileptic seizures.

Indexed as

EpilepsyNeurocysticercosisCross-Sectional StudiesHumansQuality of LifeSeizuresSurveys and QuestionnairesCysticercosisEpilepsyNeurocysticercosisPeruQOLIE-31 scoreQuality of life

Identifiers

PMID35483205
PMCPMC9879681
OpenAlexW4224885299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.