ArticleScience (New York, N.Y.)2022
Rabies shows how scale of transmission can enable acute infections to persist at low prevalence.
Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- One Health genomic surveillance reveals structured urban rabies transmission and major surveillance gaps.bioRxiv : the preprint server for biology · 2026Article
- Higher free-roaming dog density sustains rabies virus transmission in Haiti.Scientific reports · 2026Article
- Animal networks become more connected in densely populated areas.Nature ecology & evolution · 2025Article
- Density-dependent network structuring within and across wild animal systems.Nature ecology & evolution · 2025Article
- Generalizing an outbreak cluster detection method for two groups: an application to rabies.Royal Society open science · 2025Article
- Rabies Surveillance in Mainland Tanzania: A Scoping Review of Animal Rabies Occurrences (1993-2023).Pathogens (Basel, Switzerland) · 2025Article
- Exploring one health-based strategies for rabies elimination: Overview and future prospects.PLoS neglected tropical diseases · 2025Review
- Improved effectiveness of vaccination campaigns against rabies by reducing spatial heterogeneity in coverage.PLoS biology · 2025Article
- The evolution and epidemiology of H3N2 canine influenza virus after 20 years in dogs.Epidemiology and infection · 2025Article
- Challenging a paradigm: Staggered versus single-pulse mass dog vaccination strategy for rabies elimination.PLoS computational biology · 2025Article
- Combining genomics and epidemiology to investigate a zoonotic outbreak of rabies in Romblon Province, Philippines.Nature communications · 2024Article
- Examining the molecular clock hypothesis for the contemporary evolution of the rabies virus.PLoS pathogens · 2024Article
- Molecular characterisation of human rabies in Tanzania and Kenya: a case series report and phylogenetic investigation.Infectious diseases of poverty · 2024Article
- Empirical and model-based evidence for a negligible role of cattle in peste des petits ruminants virus transmission and eradication.Communications biology · 2024Article
- Kenyan Free-Tailed Bats Demonstrate Seasonal Birth Pulse Asynchrony with Implications for Virus Maintenance.EcoHealth · 2024Article
- Rabies vaccinations at the rural-urban divide: successes and barriers to dog rabies vaccination programs from a rural and urban campaign in Zambia.Frontiers in veterinary science · 2024Article
- Testing novel facial recognition technology to identify dogs during vaccination campaigns.Scientific reports · 2023Article
- Identification of dynamical changes of rabies transmission under quarantine: Community-based measures towards rabies elimination.PLoS computational biology · 2023Article
- Tracking lethal threat: in-depth review of rabies.Open veterinary journal · 2023Review
- An extended period of elevated influenza mortality risk follows the main waves of influenza pandemics.Social science & medicine (1982) · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
How acute pathogens persist and what curtails their epidemic growth in the absence of acquired immunity remains unknown. Canine rabies is a fatal zoonosis that circulates endemically at low prevalence among domestic dogs in low- and middle-income countries. We traced rabies transmission in a population of 50,000 dogs in Tanzania from 2002 to 2016 and applied individual-based models to these spatially resolved data to investigate the mechanisms modulating transmission and the scale over which they operate. Although rabies prevalence never exceeded 0.15%, the best-fitting models demonstrated appreciable depletion of susceptible animals that occurred at local scales because of clusters of deaths and dogs already incubating infection. Individual variation in rabid dog behavior facilitated virus dispersal and cocirculation of virus lineages, enabling metapopulation persistence. These mechanisms have important implications for prediction and control of pathogens that circulate in spatially structured populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.