Evidence map›Paper›PMID 35482649›Full record

ArticlePloS one2022

Adolescent individual, school, and neighborhood influences on young adult hypertension risk.

Hoda S Abdel Magid, Carly E Milliren, Kathryn Rice, Nina Molanphy, Kennedy Ruiz, Holly C Gooding, Tracy K Richmond, Michelle C Odden, Jason M Nagata

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Observational
  5. Hypertension in children and adolescents: perspectives in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hoda S Abdel MagidDepartment of Epidemiology and Population Health, Stanford University, Stanford, California, United States of America.ORCID 0000-0002-5270-1197
Carly E MillirenInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Kathryn RicePublic Health Sciences Program, Santa Clara University, Santa Clara, California, United States of America.
Nina MolanphyPublic Health Sciences Program, Santa Clara University, Santa Clara, California, United States of America.
Kennedy RuizPublic Health Sciences Program, Santa Clara University, Santa Clara, California, United States of America.
Holly C GoodingDivision of General Pediatrics and Adolescent Medicine, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Tracy K RichmondDivision of Adolescent and Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Michelle C OddenDepartment of Epidemiology and Population Health, Stanford University, Stanford, California, United States of America.
Jason M NagataDivision of Adolescent & Young Adult Medicine, University of California, San Francisco, San Francisco, California, United States of America.ORCID 0000-0002-6541-0604

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VII Core ProjectU01AG071448 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT A HUMMER · 2021 to 2026
$40.2M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectU01AG071450 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AIELLO, ALLISON E, HUMMER, ROBERT A · 2021 to 2025
$16.2M
Informing national guidelines on adolescent and young adult physical activity and sedentary behavior to prevent cardiovascular diseaseK08HL159350 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGATA, JASON M · 2021 to 2025
$869k
NHLBI NIH HHS K08 HL159350NIA NIH HHS U01 AG071448NIA NIH HHS U01 AG071450NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

backgroundGeographic and contextual socioeconomic risk factors in adolescence may be more strongly associated with young adult hypertension than individual-level risk factors. This study examines the association between individual, neighborhood, and school-level influences during adolescence on young adult blood pressure.

methodsData were analyzed from the National Longitudinal Study of Adolescent to Adult Health (1994-1995 aged 11-18 and 2007-2008 aged 24-32). We categorized hypertension as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg. Secondary outcomes included continuous systolic and diastolic blood pressure. We fit a series of cross-classified multilevel models to estimate the associations between young adulthood hypertension with individual-level, school-level, and neighborhood-level factors during adolescence (i.e., fixed effects) and variance attributable to each level (i.e., random effects). Models were fit using Bayesian estimation procedures. For linear models, intra-class correlations (ICC) are reported for random effects.

resultsThe final sample included 13,911 participants in 128 schools and 1,917 neighborhoods. Approximately 51% (7,111) young adults were hypertensive. Individual-level characteristics-particularly older ages, Non-Hispanic Black race, Asian race, male sex, BMI, and current smoking-were associated with increased hypertension. Non-Hispanic Black (OR = 1.21; 95% CI: 1.03-1.42) and Asian (OR = 1.28; 95% CI: 1.02-1.62) students had higher odds of hypertension compared to non-Hispanic White students. At the school level, hypertension was associated with the percentage of non-Hispanic White students (OR for 10% higher = 1.06; 95% CI: 1.01-1.09). Adjusting for individual, school, and neighborhood predictors attenuated the ICC for both the school (from 1.4 null to 0.9 fully-adjusted) and neighborhood (from 0.4 to 0.3).

conclusionWe find that adolescents' schools and individual-level factors influence young adult hypertension, more than neighborhoods. Unequal conditions in school environments for adolescents may increase the risk of hypertension later in life. Our findings merit further research to better understand the mechanisms through which adolescents' school environments contribute to adult hypertension and disparities in hypertension outcomes later in life.

Indexed as

HypertensionResidence CharacteristicsAdolescentAdultBayes TheoremHumansLongitudinal StudiesMaleSchoolsYoung Adult

Identifiers

PMID35482649
PMCPMC9049504

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.