Evidence map›Paper›PMID 35482211›Full record

ArticleCellular and molecular life sciences : CMLS2022

SMA

Abhijit Nirwane, Yao Yao

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Rediscovery of pericytes within the neurovascular unit for cerebral ischemia/reperfusion injury.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. A dispensable role of mural cell-derived laminin-Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  16. Signaling Role of Pericytes in Vascular Health and Tissue Homeostasis.International journal of molecular sciences · 2024
    Review
  17. Review
  18. A dispensable role of oligodendrocyte-derived laminin-α5 in brain homeostasis and intracerebral hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Abhijit NirwaneDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC8, Tampa, FL, 33612, USA.
Yao YaoDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC8, Tampa, FL, 33612, USA. yao7@usf.edu.ORCID http://orcid.org/0000-0001-8020-9696
University of South Florida · US

Funding

Endothelial laminin in blood brain barrier regulationR01HL146574 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI YAO, YAO · 2019 to 2023
$1.9M
The roles of pericyte-derived laminin in neurovascular function and neurodegenerationRF1AG065345 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI YAO, YAO · 2021 to 2021
$1.8M
Screening and identification of pericyte-specific and subpopulation-specific markersR21AG064422 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI YAO, YAO · 2020 to 2021
$415k
Cell-specific changes of laminin expression in the CNS in Alzheimer’s diseaseR21AG073862 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI YAO, YAO · 2021 to 2021
$411k
NHLBI NIH HHS R01 HL146574NHLBI NIH HHS R01HL146574NIA NIH HHS R21 AG064422NIA NIH HHS R21AG064422NIA NIH HHS R21 AG073862NIA NIH HHS R21AG073862NIA NIH HHS RF1 AG065345NIA NIH HHS RF1AG065345
6 · The paper itself

Abstract

Pericytes are multipotent perivascular cells that play important roles in CNS injury. However, controversial findings exist on how pericytes change and whether they differentiated into microglia-like cells after ischemic stroke. This discrepancy is mainly due to the lack of pericyte-specific markers: the "pericyte" population identified in previous studies contained vascular smooth muscle cells (vSMCs) and/or fibroblasts. Therefore, it remains unclear which cell type differentiates into microglia-like cells after stroke. In this study, lineage-tracing technique was used to mark α-smooth muscle actin (SMA)

Indexed as

Ischemic StrokeStrokeBrainHumansMacrophagesMicrogliaPericytesCol1α1FibroblastsIschemic strokePDGFRβPericytes

Identifiers

PMID35482211
PMCPMC11073453
OpenAlexW4225004812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.