Evidence map›Paper›PMID 35482152›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

BASH-GN: a new machine learning-derived questionnaire for screening obstructive sleep apnea.

Jiayan Huo, Stuart F Quan, Janet Roveda, Ao Li

Open access · greenAbstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Obstructive sleep apnea: Proposed scoring system.World journal of methodology · 2026
    Review
  3. Article
  4. A novel machine learning model for screening the risk of obstructive sleep apnea using craniofacial photography with questionnaires.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  5. Review
  6. Prediction of early myocardial damage in obstructive sleep apnea patients using combined logistic regression and QUEST decision tree models.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jiayan HuoBiomedical Engineering, The University of Arizona, Tucson, AZ, USA.
Stuart F QuanDivision of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Janet RovedaBiomedical Engineering, The University of Arizona, Tucson, AZ, USA.
Ao LiDepartment of Electrical and Computer Engineering, The University of Arizona, 1230 E Speedway Blvd, Tucson, AZ, 85719, USA. aoli1@arizona.edu.ORCID 0000-0002-1927-8606
University of Arizona · USBrigham and Women's Hospital · US

Funding

Explainable Deep Learning Approach for Automatic Arousal and Sleep Stages Scoring, and Knowledge DiscoveryR21HL159661 · NHLBI · UNIVERSITY OF ARIZONA · PI LI, AO · 2021 to 2022
$230k
NHLBI NIH HHS R21 HL159661NHLBI NIH HHS R21HL159661-01
6 · The paper itself

Abstract

purposeThis study aimed to develop a machine learning-based questionnaire (BASH-GN) to classify obstructive sleep apnea (OSA) risk by considering risk factor subtypes.

methodsParticipants who met study inclusion criteria were selected from the Sleep Heart Health Study Visit 1 (SHHS 1) database. Other participants from the Wisconsin Sleep Cohort (WSC) served as an independent test dataset. Participants with an apnea hypopnea index (AHI) ≥ 15/h were considered as high risk for OSA. Potential risk factors were ranked using mutual information between each factor and the AHI, and only the top 50% were selected. We classified the subjects into 2 different groups, low and high phenotype groups, according to their risk scores. We then developed the BASH-GN, a machine learning-based questionnaire that consists of two logistic regression classifiers for the 2 different subtypes of OSA risk prediction.

resultsWe evaluated the BASH-GN on the SHHS 1 test set (n = 1237) and WSC set (n = 1120) and compared its performance with four commonly used OSA screening questionnaires, the Four-Variable, Epworth Sleepiness Scale, Berlin, and STOP-BANG. The model outperformed these questionnaires on both test sets regarding the area under the receiver operating characteristic (AUROC) and the area under the precision-recall curve (AUPRC). The model achieved AUROC (SHHS 1: 0.78, WSC: 0.76) and AUPRC (SHHS 1: 0.72, WSC: 0.74), respectively. The questionnaire is available at https://c2ship.org/bash-gn .

conclusionConsidering OSA subtypes when evaluating OSA risk may improve the accuracy of OSA screening.

Indexed as

Mass ScreeningSleep Apnea, ObstructiveHumansMachine LearningROC CurveSurveys and QuestionnairesMachine learningObstructive sleep apneaQuestionnaireScreening

Identifiers

PMID35482152
PMCPMC11577832
OpenAlexW4226425732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.