Evidence map›Paper›PMID 35482059›Full record

ReviewSeminars in immunopathology2022

Liver-resident memory T cells: life in lockdown.

Laura J Pallett, Mala K Maini

Open access · hybridAbstract readReview
In one paragraph

Review in Seminars in immunopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Tissue-resident memory CD8Nature reviews. Gastroenterology & hepatology · 2025
    Review
  5. Article
  6. Article
  7. Expansion of CD103Frontiers in immunology · 2025
    Article
  8. Article
  9. Article
  10. CXCR6JHEP reports : innovation in hepatology · 2024
    Article
  11. Immunological Monitoring in Hepatitis C Virus Controlled Human Infection Model.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  12. Insights into phenotypic and functional CD8Immunological reviews · 2023
    Review
  13. Tissue CD14Nature · 2023
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Laura J PallettInstitute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Pears Building, Rowland Hill St, London, NW3 2PP, UK. laura.pallett@ucl.ac.uk.ORCID 0000-0002-4161-9462
Mala K MainiInstitute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Pears Building, Rowland Hill St, London, NW3 2PP, UK. m.maini@ucl.ac.uk.ORCID 0000-0001-6384-1462
Institute of Infection and Immunity · CA

Funding

Cancer Research UK 26813Medical Research Council MR/V02423X/1Wellcome TrustWellcome Trust 214191/Z/18/Z
6 · The paper itself

Abstract

A subset of memory T cells has been identified in the liver with a tissue-resident profile and the capacity for long-term 'lockdown'. Here we review how they are retained in, and adapted to, the hepatic microenvironment, including its unique anatomical features and metabolic challenges. We describe potential interactions with other local cell types and the need for a better understanding of this complex bidirectional crosstalk. Pathogen or tumour antigen-specific tissue-resident memory T cells (T

Indexed as

Immunologic MemoryNeoplasmsCD8-Positive T-LymphocytesHumansImmunologic SurveillanceLiverMemory T CellsTumor MicroenvironmentAdaptive immunityCD4+ TRMCD8+ TRMLiverMetabolic adaptationTissue-resident

Identifiers

PMID35482059
PMCPMC9708784
OpenAlexW4225004501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.