ArticleAdvanced healthcare materials2022
Mobile Nanobots for Prevention of Root Canal Treatment Failure.
Article in Advanced healthcare materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 49 citations in OpenAlex.
- Protocols to evaluate the antibacterial and irrigation efficacy of new root canal irrigants: A systematic review of ex vivo studies.The Japanese dental science review · 2026Review
- Magnetic induction heating: where will the field go next?Chemical Society reviews · 2026Review
- Field-Driven Active Colloids as Distributed Micromachines: Bridging Physics, Control, and Function Across Length Scales.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Unlocking miniature brilliance: micro/nanorobots for advanced dental theranostics.Journal of nanobiotechnology · 2026Review
- Precision endodontics with nanorobots: Targeted antimicrobial and regenerative strategies.Journal of conservative dentistry and endodontics · 2026Article
- Magnetic Field-Driven Strategies for Biofilm Disruption: From Iron Oxide Nanoparticles to Adaptive Swarms of Magnetic Microrobots.ACS nano · 2026Review
- Antimicrobial effectiveness of intracanal medicaments againstFrontiers in oral health · 2026Review
- Directed Self-Assembly of Magnetic Bioceramic Deep Inside Dentinal Tubules May Alleviate Dental Hypersensitivity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Technology Roadmap of Micro/Nanorobots.ACS nano · 2025Review
- Stable and Highly Steerable Magnetic Nanorobots Demonstrate Therapeutical Functionality in Crowded Biological Media.ACS nano · 2025Article
- Nanozyme-Shelled Microcapsules for Targeting Biofilm Infections in Confined Spaces.Advanced healthcare materials · 2025Article
- Nanotherapies Based on ROS Regulation in Oral Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Anisotropy, topography and non-newtonian properties of cellular interiors probed by helical magnetic nanobots.Journal of micro-bio robotics · 2025Article
- Microrobotics in endodontics: A perspective.International endodontic journal · 2024Review
- Dual-Fuel Propelled Nanomotors with Two-Stage Permeation for Deep Bacterial Infection in the Treatment of Pulpitis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Thermosensitive hydrogel with programmed dual-octenidine release combating biofilm for the treatment of apical periodontitis.Regenerative biomaterials · 2024Article
- Application of Nanomaterials in Endodontics.BME frontiers · 2024Review
- Nanobots: An endodontist saviour.Bioinformation · 2024Article
- Current status and future application of electrically controlled micro/nanorobots in biomedicine.Frontiers in bioengineering and biotechnology · 2024Review
- Micro-/nanoscale robotics for chemical and biological sensing.Lab on a chip · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Millions of root canal treatments fail worldwide due to remnant bacteria deep in the dentinal tubules located within the dentine tissue of human teeth. The complex and narrow geometry of the tubules renders current techniques relying on passive diffusion of antibacterial agents ineffective. Here, the potential of actively maneuvered nanobots is investigated to disinfect dentinal tubules, which can be incorporated during a standard root canal procedure. It is demonstrated that magnetically driven nanobots can reach the depths of the tubules not possible with current clinical practices. Subtle alterations of the magnetic drive allow both deep implantations of the nanobots isotopically distributed throughout the dentine and spatially controlled recovery from selected regions, further supported by numerical simulations. Finally, the integration of bactericidal therapeutic modality with the nanobots is demonstrated, thereby validating the tremendous potential of nanobots in dentistry and nanomedicine in general.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.