Trial reportIndoor air2022
Portable air cleaners and residential exposure to SARS-CoV-2 aerosols: A real-world study.
Trial report in Indoor air, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Managing infectious aerosols to counter engineered pandemics: Current recommendations and future research.Risk analysis : an official publication of the Society for Risk Analysis · 2025Guideline
- Non-pharmaceutical interventions for COVID-19: a systematic review on environmental control measures.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023Pooled it
- Reaction to at-home air purifiers installed to reduce traffic-related air pollution in near-highway residences.Trials · 2024Trial
- Portable air cleaners and residential exposure to SARS-CoV-2 aerosols: A real-world study.Indoor air · 2022Trial
- Detection of SARS-CoV-2 RNA on air purifier filters in university spaces without symptomatic or confirmed cases.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2025Article
- Factors Affecting Reduction of Infectious Aerosols by Far-UVC and Portable HEPA Air Cleaners.ACS ES&T air · 2025Article
- Evaluation of the decontamination efficacy of a portable air cleaner using 275-nm UVC-LED radiation against airborne Coronavirus and Influenza virus.GMS hygiene and infection control · 2025Article
- Emergency Knowledge Translation, COVID-19 and indoor air: evaluating a virtual ventilation and filtration consultation program for community spaces in Ontario.BMC public health · 2024Article
- Air Cleaners and Respiratory Infections in Schools: A Modeling Study Based on Epidemiologic, Environmental, and Molecular Data.Open forum infectious diseases · 2024Article
- Virus removal by high-efficiency air (HEPA) filters and filtration capacity enhancement by nanotextiles: a pilot study.Folia microbiologica · 2024Article
- Real-World Effectiveness of Portable Air Cleaners in Reducing Home Particulate Matter Concentrations.Aerosol and air quality research · 2024Article
- Air Change Rate and SARS-CoV-2 Exposure in Hospitals and Residences: A Meta-Analysis.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2024Article
- Air cleaners and respiratory infections in schools: A modeling study using epidemiological, environmental, and molecular data.medRxiv : the preprint server for health sciences · 2023Article
- Implemented indoor airborne transmission mitigation strategies during COVID-19: a systematic review.Journal of environmental health science & engineering · 2023Review
- Efficacy of Grignard Pure to Inactivate Airborne Phage MS2, a Common SARS-CoV-2 Surrogate.Environmental science & technology · 2023Article
- Indoor air surveillance and factors associated with respiratory pathogen detection in community settings in Belgium.Nature communications · 2023Article
- Development of a high-speed bioaerosol elimination system for treatment of indoor air.Building and environment · 2023Article
- HEPA filters of portable air cleaners as a tool for the surveillance of SARS-CoV-2.Indoor air · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Individuals with COVID-19 who do not require hospitalization are instructed to self-isolate in their residences. Due to high secondary infection rates in household members, there is a need to understand airborne transmission of SARS-CoV-2 within residences. We report the first naturalistic intervention study suggesting a reduction of such transmission risk using portable air cleaners (PACs) with HEPA filters. Seventeen individuals with newly diagnosed COVID-19 infection completed this single-blind, crossover, randomized study. Total and size-fractionated aerosol samples were collected simultaneously in the self-isolation room with the PAC (primary) and another room (secondary) for two consecutive 24-h periods, one period with HEPA filtration and the other with the filter removed (sham). Seven out of sixteen (44%) air samples in primary rooms were positive for SARS-CoV-2 RNA during the sham period. With the PAC operated at its lowest setting (clean air delivery rate [CADR] = 263 cfm) to minimize noise, positive aerosol samples decreased to four out of sixteen residences (25%; p = 0.229). A slight decrease in positive aerosol samples was also observed in the secondary room. As the world confronts both new variants and limited vaccination rates, our study supports this practical intervention to reduce the presence of viral aerosols in a real-world setting.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.