Evidence map›Paper›PMID 35481715›Full record

ArticleJournal of veterinary internal medicine2022

Association of hydromyelia and acute compressive myelopathy caused by intervertebral disc extrusion in dogs.

Philippa J Johnson, Amy B Todd-Donato, Andrew D Miller, Yu Wang, Chris Holm, Carolina I Panisello-Manterola, Claudia S Colón Acevedo, Jonathan H Wood

Open access · goldAbstract readObservational Study, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Philippa J JohnsonDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-4558-0745
Amy B Todd-DonatoDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
Andrew D MillerDepartment of Biomedical Sciences, Cornell University, Ithaca, New York, USA.
Yu WangDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
Chris HolmDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
Carolina I Panisello-ManterolaDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
Claudia S Colón AcevedoDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
Jonathan H WoodDepartment of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHydromyelia is a common magnetic resonance imaging (MRI) finding associated with compressive myelopathy caused by intervertebral disc extrusion (IVDE).

objectivesTo describe the MRI features of hydromyelia and explore its relationship to clinical history, neurological severity, and the duration of cord compression. ANIMALS: Ninety-one client-owned dogs with a focal compressive myelopathy secondary to thoracolumbar IVDE.

methodsA retrospective observational study was conducted in which MRIs were blindly evaluated to grade and localize hydromyelia and measure the degree of spinal cord compression. Duration and severity of clinical signs were recorded. Differences between hydromyelia grades in these variables were statistically assessed using a Wilcoxon and Kruskal Wallis test. Receiver operator curve analysis was used to determine the sensitivity and specificity for duration of clinical signs to predict the presence of hydromyelia.

resultsHydromyelia was identified at sites of IVDE in 84 of 91 dogs. An absence of hydromyelia was associated a with statistically longer duration of clinical signs (mean 73.1, IQR 76 days) when compared to cases with mild (mean 17.7, IQR 7.25 days, P = .006) or severe (mean 17.9, IQR 10.25 days, P = .006) hydromyelia. Duration of clinical signs <14 days was 78.6% sensitive and 85.7% specific for predicting the presence of hydromyelia. CONCLUSIONS AND CLINICAL IMPORTANCE: The MRI finding of hydromyelia might be a predictor of lesion chronicity in focal IVDE, helping to guide planning of hemilaminectomy surgery.

Indexed as

Dog DiseasesIntervertebral DiscIntervertebral Disc DisplacementSpinal Cord CompressionAnimalsDogsLaminectomyMagnetic Resonance ImagingRetrospective StudiescaninechronicCSFobstructive hydromyeliasyringohydromyelia

Identifiers

PMID35481715
PMCPMC9151477
OpenAlexW4224999600

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.