Evidence map›Paper›PMID 35481649›Full record

ArticleProtein science : a publication of the Protein Society2022

Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.

Jordi C J Hintzen, Huida Ma, Hao Deng, Apolonia Witecka, Steffen B Andersen, Jakub Drozak, Hong Guo, Ping Qian, Haitao Li, Jasmin Mecinović

Open access · hybridAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Histidine Ethylation by Histidine Methyltransferases SETD3 and METTL9.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Substrate selectivity of human histidine methyltransferase METTL9.Protein science : a publication of the Protein Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.Protein science : a publication of the Protein Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Jordi C J HintzenDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
Huida MaMOE Key Laboratory of Protein Sciences, Beijing Frontier Research Center for Biological Structure, School of Medicine, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, China.
Hao DengChemistry and Materials Science Faculty, Shandong Agricultural University, Tai'an, Shandong, China.
Apolonia WiteckaDepartment of Metabolic Regulation, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Steffen B AndersenDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
Jakub DrozakDepartment of Metabolic Regulation, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Hong GuoDepartment of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee, USA.
Ping QianChemistry and Materials Science Faculty, Shandong Agricultural University, Tai'an, Shandong, China.
Haitao LiMOE Key Laboratory of Protein Sciences, Beijing Frontier Research Center for Biological Structure, School of Medicine, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, China.
Jasmin MecinovićDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-5559-3822
University of Southern Denmark · DKCenter for Life Sciences · CNShandong Agricultural University · CNUniversity of Warsaw · PLOak Ridge National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actin histidine N

Indexed as

ActinsMethyltransferasesHistidineHistone MethyltransferasesHumansMethylationActinsHistidineHistone MethyltransferasesMethyltransferasesSETD3 protein, humanbiocatalysishistidinemethylationSETD3β-actin

Identifiers

PMID35481649
PMCPMC9004244
OpenAlexW4223455663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.