Evidence map›Paper›PMID 35481596›Full record

ArticleMagnetic resonance in medicine2022

Free-breathing self-gated continuous-IR spiral T1 mapping: Comparison of dual flip-angle and Bloch-Siegert B1-corrected techniques.

Ruixi Zhou, Junyu Wang, Daniel S Weller, Yang Yang, John P Mugler, Michael Salerno

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Motion-compensated TFrontiers in cardiovascular medicine · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruixi ZhouDepartment of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.ORCID 0000-0001-9231-4987
Junyu WangDepartment of Biomedical Engineering, University of Virginia Health System, Charlottesville, Virginia, USA.ORCID 0000-0001-8314-4525
Daniel S WellerKLA Tencor, GPG/AI, Charlottesville, Virginia, USA.ORCID 0000-0001-9818-7325
Yang YangBiomedical Engineering and Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
John P MuglerRadiology & Medical Imaging, Biomedical Engineering, University of Virginia Health System, Charlottesville, Virginia, USA.
Michael SalernoDepartment of Medicine, Cardiovascular Medicine and Department of Radiology, Cardiovascular Imaging, Stanford University, Palo Alto, California, USA.

Funding

High-Resolution Whole Heart Quantitative CMR Perfusion Imaging in Ischemic Heart DiseaseR01HL131919 · NHLBI · UNIVERSITY OF VIRGINIA · PI ENNIS, DANIEL B · 2017 to 2021
$3.5M
Rapid Free-Breathing Self-Gated Spiral Pulse Sequences for Simultaneous Cine and T1 mappingR01HL155962 · NHLBI · UNIVERSITY OF VIRGINIA · PI SALERNO, MICHAEL · 2021 to 2024
$2.1M
NHLBI NIH HHS R01 HL155962NIH HHS R01 HL131919NIH HHS R01 HL155962
6 · The paper itself

Abstract

purposeTo develop a B1-corrrected single flip-angle continuous acquisition strategy with free-breathing and cardiac self-gating for spiral T1 mapping, and compare it to a previous dual flip-angle technique.

methodsData were continuously acquired using a spiral-out trajectory, rotated by the golden angle in time. During the first 2 s, off-resonance Fermi RF pulses were applied to generate a Bloch-Siegert shift B1 map, and the subsequent data were acquired with an inversion RF pulse applied every 4 s to create a T1* map. The final T1 map was generated from the B1 and the T1* maps by using a look-up table that accounted for slice profile effects, yielding more accurate T1 values. T1 values were compared to those from inversion recovery (IR) spin echo (phantom only), MOLLI, SAturation-recovery single-SHot Acquisition (SASHA), and previously proposed dual flip-angle results. This strategy was evaluated in a phantom and 25 human subjects.

resultsThe proposed technique showed good agreement with IR spin-echo results in the phantom experiment. For in-vivo studies, the proposed technique and the previously proposed dual flip-angle method were more similar to SASHA results than to MOLLI results.

conclusionsB1-corrected single flip-angle T1 mapping successfully acquired B1 and T1 maps in a free-breathing, continuous-IR spiral acquisition, providing a method with improved accuracy to measure T1 using a continuous Look-Locker acquisition, as compared to the previously proposed dual excitation flip-angle technique.

Indexed as

Magnetic Resonance ImagingRespirationHeartHumansPhantoms, ImagingReproducibility of ResultsB1 mappingcardiac MRIdictionary learningfree-breathingmotion-correctionself-gatingspiral trajectoryT1 mapping

Identifiers

PMID35481596
PMCPMC9325422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.