Evidence map›Paper›PMID 35481403›Full record

ArticleSystems biology in reproductive medicine2022

Sex chromosome DSD individuals with mosaic 45,X0 and aberrant Y chromosomes in 46,XY cells: distinct gender phenotypes and germ cell tumour risks

Peter H Vogt, Banu Besikoglu, Markus Bettendorf, Petra Frank-Herrmann, Jutta Zimmer, Urike Bender, Sabine Knauer-Fischer, Daniela Choukair, Peter Sinn, Helmuth-Guenther Doerr and 4 more

Open access · greenAbstract read
In one paragraph

Article in Systems biology in reproductive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Peter H VogtDivision of Reproduction Genetics, Department of Gynaecological Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Heidelberg, Germany.
Banu BesikogluDivision of Reproduction Genetics, Department of Gynaecological Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Heidelberg, Germany.
Markus BettendorfDivision of Paediatric Endocrinology and Diabetes, Children Hospital, University of Heidelberg, Heidelberg, Germany.
Petra Frank-HerrmannDepartment of Gynaecological Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Heidelberg, Germany.
Jutta ZimmerDivision of Reproduction Genetics, Department of Gynaecological Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Heidelberg, Germany.
Urike BenderDivision of Reproduction Genetics, Department of Gynaecological Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Heidelberg, Germany.
Sabine Knauer-FischerDivision of Paediatric Endocrinology and Diabetes, Children Hospital, University of Heidelberg, Heidelberg, Germany.
Daniela ChoukairDivision of Paediatric Endocrinology and Diabetes, Children Hospital, University of Heidelberg, Heidelberg, Germany.
Peter SinnDivision of Gynaecopathology, Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Helmuth-Guenther DoerrChildren Hospital; University of Erlangen, Erlangen, Germany.
Joachim WoelfleChildren Hospital; University of Erlangen, Erlangen, Germany.
Peter H HeidemannChildren Hospital Augsburg I, Academic Hospital of University of Munich, Augsburg, Germany.
Yun-Fai Chris LauDepartment of Medicine, VA Medical Center 111C5, University of California, San Francisco, USA.
Thomas StrowitzkiDepartment of Gynaecological Endocrinology & Infertility Disorders, Women Hospital, University of Heidelberg, Heidelberg, Germany.
Heidelberg University · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity Hospital Heidelberg · DEUniversity Hospital Augsburg · DEUniversity of California, San Francisco · US

Funding

Molecular Mechanisms of a Male-Specific Positive Feedback Loop in Liver CancerI01BX004446 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI LAU, YUN-FAI CHRIS · 2019 to 2023
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BLRD Research Career Scientist Award ApplicationIK6BX004854 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI LAU, YUN-FAI CHRIS · 2020 to 2025
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BLRD VA I01 BX004446BLRD VA IK6 BX004854
6 · The paper itself

Abstract

"

Indexed as

GonadoblastomaNeoplasms, Germ Cell and EmbryonalOvarian NeoplasmsSex Chromosome Disorders of Sex DevelopmentChromosome BreakageChromosomes, Human, YDEAD-box RNA HelicasesFemaleHumansMaleMinor Histocompatibility AntigensPhenotypeDDX3Y protein, humanDEAD-box RNA HelicasesMinor Histocompatibility Antigens45X/46XY mosaic DSDdi-centric Y chromosomeGerm cell tumour riskOCT3/4 expression GBY expression

Identifiers

PMID35481403
PMCPMC10284372
OpenAlexW4225087082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.