Evidence map›Paper›PMID 35481289›Full record

ArticleOncoimmunology2022

Tumor-associated macrophages promote intratumoral conversion of conventional CD4

Kevin Kos, Camilla Salvagno, Max D Wellenstein, Muhammad A Aslam, Denize A Meijer, Cheei-Sing Hau, Kim Vrijland, Daphne Kaldenbach, Elisabeth A M Raeven, Martina Schmittnaegel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  4. SSTNSignal transduction and targeted therapy · 2026
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  20. Overcoming fixation and permeabilization challenges in flow cytometry by optical barcoding and multi-pass acquisition.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Kevin KosDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Camilla SalvagnoDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Max D WellensteinDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Muhammad A AslamDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Denize A MeijerDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Cheei-Sing HauDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0002-4728-4886
Kim VrijlandDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Daphne KaldenbachDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Elisabeth A M RaevenDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Martina SchmittnaegelRoche Innovation Center Munich, Roche Pharma Research and Early Development, Penzberg, Germany.
Carola H RiesRoche Innovation Center Munich, Roche Pharma Research and Early Development, Penzberg, Germany.
Karin E de VisserDivision of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0002-0293-868X
The Netherlands Cancer Institute · NLLeiden University Medical Center · NLRoche (Switzerland) · CHCornell University · USRoyal Netherlands Academy of Arts and Sciences · NL

Funding

European Research Council 615300
6 · The paper itself

Abstract

While regulatory T cells (T

Indexed as

Breast NeoplasmsT-Lymphocytes, RegulatoryFemaleHumansImmune ToleranceProgrammed Cell Death 1 ReceptorTumor-Associated MacrophagesTumor MicroenvironmentProgrammed Cell Death 1 ReceptorBreast cancer immunologyregulatory T cellsT cell plasticitytumor-associated macrophages

Identifiers

PMID35481289
PMCPMC9037432
OpenAlexW4223900762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.