Evidence map›Paper›PMID 35481109›Full record

ArticleRSC advances2022

Rational synthesis of IR820-albumin complex for NIR-II fluorescence imaging-guided surgical treatment of tumors and gastrointestinal obstruction.

Xinyu Feng, Yuan Cao, Pengrui Zhuang, Ran Cheng, Xuejun Zhang, Hong Liu, Guohe Wang, Shao-Kai Sun

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xinyu FengSchool of Medical Imaging, Tianjin Medical University Tianjin 300203 China wangguohe@tmu.edu.cn shaokaisun@tmu.edu.cn.
Yuan CaoSchool of Medical Imaging, Tianjin Medical University Tianjin 300203 China wangguohe@tmu.edu.cn shaokaisun@tmu.edu.cn.
Pengrui ZhuangDepartment of Radiology, The Second Hospital of Tianjin Medical University Tianjin 300211 China.
Ran ChengSchool of Medical Imaging, Tianjin Medical University Tianjin 300203 China wangguohe@tmu.edu.cn shaokaisun@tmu.edu.cn.
Xuejun ZhangSchool of Medical Imaging, Tianjin Medical University Tianjin 300203 China wangguohe@tmu.edu.cn shaokaisun@tmu.edu.cn.
Hong LiuThe Second Surgical Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer Tianjin 300060 China liuhongzhang0101@163.com.
Guohe WangSchool of Medical Imaging, Tianjin Medical University Tianjin 300203 China wangguohe@tmu.edu.cn shaokaisun@tmu.edu.cn.
Shao-Kai SunSchool of Medical Imaging, Tianjin Medical University Tianjin 300203 China wangguohe@tmu.edu.cn shaokaisun@tmu.edu.cn.ORCID https://orcid.org/0000-0001-6136-9969
Tianjin Medical University · CNSecond Hospital of Tianjin Medical University · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IR820, an analog of FDA-approved indocyanine green, is a promising second near-infrared window (NIR-II) fluorescence probe with better NIR-II fluorescence stability and great clinical transformation potential. Moreover, its fluorescence can be further remarkably enhanced by the interaction with albumin. Therefore, it is significant to flexibly design IR820-albumin complex using endogenous or exogenetic albumin to meet the requirements of different biological applications. Herein, we show the rational synthesis of IR820-albumin complex for NIR-II fluorescence imaging-guided surgical treatment of tumors and gastrointestinal obstruction. We compared the NIR-II fluorescence imaging ability of IR820 pre-incubated with albumin or not to visualize tumors and the gastrointestinal tract

Identifiers

PMID35481109
PMCPMC9023119
OpenAlexW4225087893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.