Evidence map›Paper›PMID 35480984›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Downregulation of miR-760 Causes Human Intervertebral Disc Degeneration by Targeting the MyD88/Nuclear Factor-Kappa B Signaling Pathway.

Xueliang Cui, Yanan Li, Junping Bao, Kun Wang, Xiaotao Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xueliang CuiMedical School of Southeast University, Nanjing, China.
Yanan LiDepartment of Orthopaedics, Qingdao Women and Children's Hospital, Qingdao, China.
Junping BaoDepartment of Orthopaedics, Zhongda Hospital, Southeast University, Nanjing, China.
Kun WangDepartment of Orthopaedics, Zhongda Hospital, Southeast University, Nanjing, China.
Xiaotao WuDepartment of Orthopaedics, Zhongda Hospital, Southeast University, Nanjing, China.
Zhongda Hospital Southeast University · CNQingdao Women and Children's Hospital · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulation of microRNAs (miRNAs) plays a critical role in the development of intervertebral disc degeneration (IDD). In this study, we present evidence from

Indexed as

intervertebral disc degenerationmiR-760MyD88NF-κB signaling pathwaynucleus pulposus cells

Identifiers

PMID35480984
PMCPMC9035519
OpenAlexW4223586817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.