Evidence map›Paper›PMID 35480859›Full record

ArticleRegenerative biomaterials2022

Integrating pore architectures to evaluate vascularization efficacy in silicate-based bioceramic scaffolds.

Fanghui Wu, Jun Yang, Xiurong Ke, Shuo Ye, Zhaonan Bao, Xianyan Yang, Cheng Zhong, Miaoda Shen, Sanzhong Xu, Lei Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  9. Biomedicines · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Fanghui WuDepartment of Orthopaedics, The Third Hospital Affiliated to Wenzhou Medical University & Rui'an People's Hospital, Rui'an 325200, China.
Jun YangDepartment of Orthopaedics, The Third Hospital Affiliated to Wenzhou Medical University & Rui'an People's Hospital, Rui'an 325200, China.
Xiurong KeDepartment of Orthopaedics, The Third Hospital Affiliated to Wenzhou Medical University & Rui'an People's Hospital, Rui'an 325200, China.
Shuo YeDepartment of Orthopaedics, The Third Hospital Affiliated to Wenzhou Medical University & Rui'an People's Hospital, Rui'an 325200, China.
Zhaonan BaoBio-nanomaterials and Regenerative Medicine Research Division, Zhejiang-California International Nanosystem Institute, Zhejiang University, Hangzhou 310058, China.
Xianyan YangBio-nanomaterials and Regenerative Medicine Research Division, Zhejiang-California International Nanosystem Institute, Zhejiang University, Hangzhou 310058, China.
Cheng ZhongDepartment of Orthopaedics, The First Affiliated Hospital, School of Medicine of Zhejiang University, Hangzhou 310003, China.
Miaoda ShenDepartment of Orthopaedics, The First Affiliated Hospital, School of Medicine of Zhejiang University, Hangzhou 310003, China.
Sanzhong XuDepartment of Orthopaedics, The First Affiliated Hospital, School of Medicine of Zhejiang University, Hangzhou 310003, China.
Lei ZhangDepartment of Orthopaedics, The Third Hospital Affiliated to Wenzhou Medical University & Rui'an People's Hospital, Rui'an 325200, China.
Zhongru GouBio-nanomaterials and Regenerative Medicine Research Division, Zhejiang-California International Nanosystem Institute, Zhejiang University, Hangzhou 310058, China.
Guojing YangDepartment of Orthopaedics, The Third Hospital Affiliated to Wenzhou Medical University & Rui'an People's Hospital, Rui'an 325200, China.
Ruian People's Hospital · CNZhejiang University · CNZhejiang International Studies University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pore architecture in bioceramic scaffolds plays an important role in facilitating vascularization efficiency during bone repair or orbital reconstruction. Many investigations have explored this relationship but lack integrating pore architectural features in a scaffold, hindering optimization of architectural parameters (geometry, size and curvature) to improve vascularization and consequently clinical outcomes. To address this challenge, we have developed an integrating design strategy to fabricate different pore architectures (cube, gyroid and hexagon) with different pore dimensions (∼350, 500 and 650 μm) in the silicate-based bioceramic scaffolds via digital light processing technique. The sintered scaffolds maintained high-fidelity pore architectures similar to the printing model. The hexagon- and gyroid-pore scaffolds exhibited the highest and lowest compressive strength (from 15 to 55 MPa), respectively, but the cube-pore scaffolds showed appreciable elastic modulus. Moreover, the gyroid-pore architecture contributed on a faster ion dissolution and mass decay

Indexed as

digital light processingintegrating pore architecturespore geometryprecise manufacturingvascularization

Identifiers

PMID35480859
PMCPMC9039507
OpenAlexW4200404017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.