Evidence map›Paper›PMID 35480830›Full record

ArticleRSC advances2021

Estrogenic activity of lignin-derivable alternatives to bisphenol A assessed

Alice Amitrano, Jignesh S Mahajan, LaShanda T J Korley, Thomas H Epps

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Alice AmitranoDepartment of Chemical and Biomolecular Engineering, University of Delaware Newark Delaware 19716 USA thepps@udel.edu.ORCID https://orcid.org/0000-0001-7919-2225
Jignesh S MahajanDepartment of Materials Science and Engineering, University of Delaware Newark Delaware 19716 USA.ORCID https://orcid.org/0000-0002-7739-1340
LaShanda T J KorleyDepartment of Chemical and Biomolecular Engineering, University of Delaware Newark Delaware 19716 USA thepps@udel.edu.ORCID https://orcid.org/0000-0002-8266-5000
Thomas H EppsDepartment of Chemical and Biomolecular Engineering, University of Delaware Newark Delaware 19716 USA thepps@udel.edu.ORCID https://orcid.org/0000-0002-2513-0966
Newark Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lignin-derivable bisphenols are potential alternatives to bisphenol A (BPA), a suspected endocrine disruptor; however, a greater understanding of structure-activity relationships (SARs) associated with such lignin-derivable building blocks is necessary to move replacement efforts forward. This study focuses on the prediction of bisphenol estrogenic activity (EA) to inform the design of potentially safer BPA alternatives. To achieve this goal, the binding affinities to estrogen receptor alpha (ERα) of lignin-derivable bisphenols were calculated

Identifiers

PMID35480830
PMCPMC9034231
OpenAlexW3177218331

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.