ArticleRSC advances2021
Role of polyunsaturated phospholipids in liquid-ordered and liquid-disordered phases.
Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Edible Fungal Polysaccharide-Liposome: Interfacial Interactions, Structure-Function Relationship, and Emerging Application in Oral Delivery and Functional Foods.International journal of molecular sciences · 2026Review
- Characterization of phospholipid-cholesterol bilayers as self-assembled amphiphile block polymers that contain headgroups.Physica A · 2026Article
- Polyphenols fromMembranes · 2025Article
- Eukaryotic Cell Membranes: Structure, Composition, Research Methods and Computational Modelling.International journal of molecular sciences · 2023Review
- Real Space and Time Imaging of Collective Headgroup Dipole Motions in Zwitterionic Lipid Bilayers.Membranes · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyunsaturated phospholipids interact complexly with other membrane components. We have examined pair interactions among ternary lipid bilayers composed of saturated DPPC, polyunsaturated PLePC, and cholesterol in the liquid-ordered and the liquid-disordered phases by all-atom molecular dynamics simulations. The results show that PLePC exhibits strong repulsion with DPPC and cholesterol in the liquid-disordered phase. When the bilayer changes to the liquid-ordered phase, the repulsion of PLePC with DPPC and cholesterol reduces significantly. The phase state of the bilayer which affects the order of acyl tails as well as their density distributions along the bilayer normal is a key factor regulating the role of PLePC in lipid mixtures. Polyunsaturated phospholipids play a strong repulsive role in the liquid-disordered phase but a weak role in the liquid-ordered phase.
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Registered trials
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