Evidence map›Paper›PMID 35480399›Full record

ArticleOpen medicine (Warsaw, Poland)2022

circ_0062491 alleviates periodontitis via the miR-142-5p/IGF1 axis.

Chunlin Wang, Junxia Gong, Dai Li, Xianghui Xing

RetractedAbstract readRetracted Publication
In one paragraph

Article in Open medicine (Warsaw, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Noncoding RNAs in periodontitis: Progress and perspectives (Review).International journal of molecular medicine · 2025
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Chunlin WangDepartment of Pediatric Dentistry, Nanjing Stomatological Hospital, Medical School of Nanjing University, Xuanwu District, Nanjing, Jiangsu 210000, China.
Junxia GongDepartment of First Outpatient, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Dai LiDepartment of Pediatric Dentistry, Nanjing Stomatological Hospital, Medical School of Nanjing University, Xuanwu District, Nanjing, Jiangsu 210000, China.
Xianghui XingDepartment of Pediatric Dentistry, Nanjing Stomatological Hospital, Medical School of Nanjing University, Xuanwu District, Nanjing, Jiangsu 210000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CircularRNAs (circRNAs) are collectively involved in periodontitis. The aim of this study was to explore the roles of circ_0062491 in osteogenic differentiation of PDLSCs and provide a novel method for periodontitis treatment. mRNA and protein expression levels were measured by qRT-PCR and western blotting. Alkaline phosphatase (ALP) and alizarin red S (ARS) staining were used to detect the activity of osteogenesis. Furthermore, the interactions between miR-142-5p and circ_0062491/

Indexed as

circ_0062491IGF1miR-142-5posteogenic differentiationperiodontal ligament stem cellsperiodontitis

Identifiers

PMID35480399
PMCPMC8994215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.