Evidence map›Paper›PMID 35480299›Full record

ArticleTherapeutic advances in gastroenterology2022

Efficacy and safety of endoscopic papillectomy: a multicenter, retrospective, cohort study on 227 patients.

Hannah Gondran, Nicolas Musquer, Enrique Perez-Cuadrado-Robles, Pierre Henri Deprez, François Buisson, Arthur Berger, Elodie Cesbron-Métivier, Timothee Wallenhorst, Nicolas David, Franck Cholet and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05690412 (Efficacy and Safety of Endoscopic Papillectomy in the Treatment of Ampullary Neoplasms), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05690412 unknown statusnot on this map

Efficacy and Safety of Endoscopic Papillectomy in the Treatment of Ampullary Neoplasms: a Multicenter, Retrospective, Nationwide Study.

TypeobservationalSponsorAzienda Unità Sanitaria Locale della RomagnaRan2022 to 2023Enrolled400ConditionsAmpullary Adenoma, Ampulla of Vater Adenoma, Ampullary Cancer, Ampulla of Vater CancerArmsEndoscopic Papillectomy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Endoscopic Papillectomy for Ampullary Tumors in Older Patients: Balancing Oncologic Benefit and Geriatric Risk.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Hannah GondranInstitut des Maladies de l'Appareil Digestif (IMAD), CHU Nantes, Nantes, France.
Nicolas MusquerInstitut des Maladies de l'Appareil Digestif (IMAD), CHU Nantes, Nantes, France.
Enrique Perez-Cuadrado-RoblesService de gastroentérologie, Hôpital européen Georges Pompidou, Assistance publique des hôpitaux de Paris, Paris, France.
Pierre Henri DeprezService d'hépato-gastro-entérologie, Cliniques universitaires Saint-Luc, Brussels, Belgium.
François BuissonService d'hépato-gastro-entérologie, CHU Angers, Angers, France.
Arthur BergerService d'hépato-gastro-entérologie, CHU Angers, Angers, France.ORCID https://orcid.org/0000-0003-0387-4734
Elodie Cesbron-MétivierService d'hépato-gastro-entérologie, CHU Angers, Angers, France.
Timothee WallenhorstService des Maladies de l'Appareil Digestif, CHU Pontchaillou, Université de Rennes 1, Rennes, France.
Nicolas DavidService d'hépatogastroen térologie, La Cavale Blanche, CHRU Brest, Brest, France.
Franck CholetService d'hépatogastroen térologie, La Cavale Blanche, CHRU Brest, Brest, France.
Bastien PerrotBiostatistics and Methodology Unit, Department of Clinical Research and Innovation, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Lucille QuénéhervéService d'hépatogastroen térologie, La Cavale Blanche, CHRU Brest, Brest, France.ORCID https://orcid.org/0000-0001-5443-2579
Emmanuel CoronDepartment of Gastroenterology and Hepatology, University Hospital of Geneva (HUG), rue Gabrielle Perret-Gentil 4, 1211, Genève 1205, Switzerland.
Centre Hospitalier Régional Universitaire de Brest · FRCentre Hospitalier Universitaire d'Angers · FRCentre Hospitalier Universitaire de Nantes · FRCliniques Universitaires Saint-Luc · BECentre Hospitalier Universitaire de Rennes · FRUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endoscopic papillectomy is a minimally invasive treatment for benign tumors of the ampulla of Vater or early ampullary carcinoma. However, reported recurrence rates are significant and risk factors for recurrence are unclear. Objective: The aims of this study were to evaluate the efficacy and safety of endoscopic papillectomy and to identify risk factors for recurrence and adverse events. Methods: All patients who underwent endoscopic papillectomy at five tertiary referral centers between January 2008 and December 2018 were included. Recurrence was defined as the detection of residue on one of the follow-up endoscopies. Treatment success was defined as the absence of tumor residue on the last follow-up endoscopy. Results: A total of 227 patients were included. The resections were Conclusion: Endoscopic papillectomy is an effective and relatively well-tolerated treatment for localized ampullary tumors. In this series, R1 resection, intraductal invasion, and lesion size > 2 cm were associated with local recurrence.

Indexed as

ampullary tumorendoscopic papillectomyendoscopic resectionpost-ERCP pancreatitis

Identifiers

PMID35480299
PMCPMC9036320
OpenAlexW4226373023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.