ArticleRSC advances2021
A freeze-thaw PVA hydrogel loaded with guava leaf extract: physical and antibacterial properties.
Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 70 citations in OpenAlex.
- Vinca Extract Infused Silk Fibroin Hydrogel for Treatment of Artificially Induced Diabetic Foot Ulcer in Murine Model.Cell biochemistry and biophysics · 2026Article
- Transdermal Delivery of Sonidegib via Iontophoresis from PEDOT:PSS/Gelatin Hydrogels for Basal Cell Carcinoma Skin Cancer.Pharmaceutics · 2026Article
- Plasticization of an Ageratum Conyzoides Natural Extract in Crosslinked Hydrogel: a Promising Material for Combating Wound Infection.Applied biochemistry and biotechnology · 2026Article
- Self-healing PVA/PVP micelle-hydrogel composite system for potential phenytoin repositioning in wound healing.Journal of biological engineering · 2025Article
- Bioactive Compounds from Guava Leaves (Molecules (Basel, Switzerland) · 2025Review
- Sulfonated White-Graphene for High-Performance Gel Polymer Electrolytes: The Interplay between Ion Conductivity and Rheology.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Controlled PVA Release from Chemical-Physical Interpenetrating Networks to Treat Dry Eyes.ACS omega · 2025Article
- Composite Hydrogel of Poly(vinyl alcohol) Loaded byACS omega · 2024Article
- Article
- Hydrophobic Drug Carrier from Polycaprolactone-Polymers · 2023Article
- Hydrogel for the Controlled Delivery of Bioactive Components from Extracts ofMolecules (Basel, Switzerland) · 2023Article
- Physicochemical Characteristics and Antibacterial Activities of Freeze-Thawed Polyvinyl Alcohol/Andrographolide Hydrogels.ACS omega · 2023Article
- GelMA/κ-carrageenan double-network hydrogels with superior mechanics and biocompatibility.RSC advances · 2023Article
- Design and evaluation of sodium alginate-based hydrogel dressings containing Betula utilis extract for cutaneous wound healing.Frontiers in bioengineering and biotechnology · 2023Article
- Gallic Acid-Loaded Sodium Alginate-Based (Polyvinyl Alcohol-Co-Acrylic Acid) Hydrogel Membranes for Cutaneous Wound Healing: Synthesis and Characterization.Molecules (Basel, Switzerland) · 2022Article
- Dielectric Properties and Flexibility of Polyacrylonitrile/Graphene Oxide Composite Nanofibers.ACS omega · 2022Article
- Progress in Antibacterial Hydrogel Dressing.Gels (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A polyvinyl alcohol (PVA) hydrogel loaded with guava leaf extract (GLE) has potential applications as a wound dressing with good antibacterial activity. This study succeeded in fabricating a PVA hydrogel containing GLE using the freeze-thaw (FT) method. By varying the GLE concentration, we can adjust the physical properties of the hydrogel. The addition of GLE results in a decrease in cross-linking during gelation and an increase in the pore size of the hydrogels. The increase of the pore size made the swelling increase and the mechanical strength decrease. The weight loss of the hydrogel also increases because the phosphate buffer saline (PBS) dissolves the GLE. Increasing the GLE concentration caused the Fourier-transform infrared (FTIR) absorbance peaks to widen due to hydrogen bonds formed during the FT process. The crystalline phase was transformed into an amorphous phase in the PVA/GLE hydrogel based on the X-ray diffraction (XRD) spectra. The differential scanning calorimetry (DSC) characterization showed a significant decrease in the hydrogel weight over temperatures of 30-150 °C due to the evaporation of water from the hydrogel matrix. The zone of inhibition of the PVA/GLE hydrogel increased with antibacterial activity against
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.