Evidence map›Paper›PMID 35480240›Full record

ArticleRSC advances2021

Aminomalononitrile inspired prebiotic chemistry as a novel multicomponent tool for the synthesis of imidazole and purine derivatives with anti-influenza A virus activity.

Bruno Mattia Bizzarri, Angelica Fanelli, Lorenzo Botta, Marta De Angelis, Anna Teresa Palamara, Lucia Nencioni, Raffaele Saladino

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. NiRSC advances · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Bruno Mattia BizzarriEcological and Biological Sciences Department (DEB), University of Tuscia Via S. Camillo de Lellis snc 01100 Viterbo Italy bm.bizzarri@unitus.it fanelli.angelica@gmail.com lorenzo.botta@unitus.it saladino@unitus.it.ORCID https://orcid.org/0000-0001-7085-5432
Angelica FanelliEcological and Biological Sciences Department (DEB), University of Tuscia Via S. Camillo de Lellis snc 01100 Viterbo Italy bm.bizzarri@unitus.it fanelli.angelica@gmail.com lorenzo.botta@unitus.it saladino@unitus.it.
Lorenzo BottaEcological and Biological Sciences Department (DEB), University of Tuscia Via S. Camillo de Lellis snc 01100 Viterbo Italy bm.bizzarri@unitus.it fanelli.angelica@gmail.com lorenzo.botta@unitus.it saladino@unitus.it.
Marta De AngelisDepartment of Public Health and Infectious Diseases, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome Piazzale Aldo Moro, 5 00185 Rome Italy marta.deangelis@uniroma1.it annateresa.palamara@uniroma1.it lucia.nencioni@uniroma1.it.
Anna Teresa PalamaraDepartment of Public Health and Infectious Diseases, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome Piazzale Aldo Moro, 5 00185 Rome Italy marta.deangelis@uniroma1.it annateresa.palamara@uniroma1.it lucia.nencioni@uniroma1.it.
Lucia NencioniDepartment of Public Health and Infectious Diseases, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome Piazzale Aldo Moro, 5 00185 Rome Italy marta.deangelis@uniroma1.it annateresa.palamara@uniroma1.it lucia.nencioni@uniroma1.it.
Raffaele SaladinoEcological and Biological Sciences Department (DEB), University of Tuscia Via S. Camillo de Lellis snc 01100 Viterbo Italy bm.bizzarri@unitus.it fanelli.angelica@gmail.com lorenzo.botta@unitus.it saladino@unitus.it.ORCID https://orcid.org/0000-0002-4420-9063
Università degli Studi della Tuscia · ITIstituto Pasteur · ITIstituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amino imidazole carbonitrile derivatives decorated with α-amino acid side-chains have been synthesized by a multicomponent microwave assisted reaction inspired by the prebiotic chemistry of aminomalononitrile as a tool for generating high chemical diversity. These compounds were used as annulation synthons for the preparation of 8,9-disubstituted-6,9-dihydro-1

Identifiers

PMID35480240
PMCPMC9040849
OpenAlexW3197305091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.