Evidence map›Paper›PMID 35480226›Full record

ReviewACS bio & med chem Au2022

Resolving the Multidecade-Long Mystery in MoaA Radical SAM Enzyme Reveals New Opportunities to Tackle Human Health Problems.

Kenichi Yokoyama, Di Li, Haoran Pang

Open access · goldAbstract readReview
In one paragraph

Review in ACS bio & med chem Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Guiding covalent catalysis enables a carbon-inserting rearrangement in molybdenum cofactor biosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Highlighting the Unique Roles of RadicalJournal of bacteriology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kenichi YokoyamaDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.
Di LiDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.
Haoran PangDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.
Duke University · US

Funding

Mechanism of cofactor biosynthesis required for chronic bacterial infectionR01GM112838 · NIGMS · DUKE UNIVERSITY · PI YOKOYAMA, KENICHI · 2015 to 2023
$2.8M
NIGMS NIH HHS R01 GM112838
6 · The paper itself

Abstract

MoaA is one of the most conserved radical

Identifiers

PMID35480226
PMCPMC9026282
OpenAlexW4200164815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.