Evidence map›Paper›PMID 35480079›Full record

ArticleEClinicalMedicine2022

Association of galactose and insulin resistance in polycystic ovary syndrome: A case-control study.

Zhijing Na, Hongyu Jiang, Yaxin Meng, Jiahui Song, Di Feng, Yuanyuan Fang, Bei Shi, Da Li

Open access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhijing NaCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
Hongyu JiangCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
Yaxin MengCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
Jiahui SongCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
Di FengEducation Center for Clinical Skill Practice, China Medical University, Shenyang 110122, China.
Yuanyuan FangCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
Bei ShiCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
Da LiCenter of Reproductive Medicine, Shengjing Hospital of China Medical University, No.36, SanHao Street, Shenyang 110004, China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polycystic ovary syndrome (PCOS) is closely linked to metabolic disorders. Recent reports have identified galactose as having strong associations with metabolic disorders, however, the correlation between galactose and PCOS remains largely unknown. Methods: The serum galactose levels of 104 patients with PCOS and 98 controls were measured, and their relationships with several metabolic parameters were analyzed. The study took place at the Center for Reproductive Medicine at Shengjing Hospital of China Medical University, Shenyang, China from July 13 to Oct 20, 2020. The relationships between serum galactose and PCOS as well as PCOS-related insulin resistance were investigated via logistic regression analyses, and the performance of serum galactose as a potential biomarker for PCOS was evaluated using receiver operating characteristic curve analysis. Findings: Higher serum galactose levels were observed in the patients with PCOS than in the controls ( Interpretation: Higher circulating galactose levels correlate with PCOS and PCOS-related insulin resistance; therefore, it may serve as a potential biomarker for patients with PCOS. These findings require further validation in a study with a larger sample size. Funding: National Natural Science Foundation of China (No. 82,071,607 and 32,100,691); LiaoNing Revitalization Talents Program (No. XLYC1907071); Fok Ying Tung Education Foundation (No. 151,039); Key Research and Development Program of Liaoning Province (NO. 2,018,225,062); Outstanding Scientific Fund of Shengjing Hospital (No. 202,003).

Indexed as

GalactoseInsulin resistanceMonosaccharidePCOS

Identifiers

PMID35480079
PMCPMC9035629
OpenAlexW4223984792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.