Evidence map›Paper›PMID 35480051›Full record

ArticleJournal of oral microbiology2022

The suppression effect of SCH-79797 on

Lingjun Zhang, Yan Shen, Lili Qiu, Fangzheng Yu, Xiangyu Hu, Min Wang, Yan Sun, Yihuai Pan, Keke Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Antibacterial effect of a dental adhesive containing SCH-79797 onFrontiers in cellular and infection microbiology · 2026
    Article
  3. Asiatic Acid Disrupts the Biofilm Virulence ofInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Zoliflodacin inhibitsFrontiers in cellular and infection microbiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Fluoride-resistantFrontiers in microbiology · 2024
    Article
  11. Article
  12. Ecological influence by colonization of fluoride-resistantFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lingjun ZhangSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yan ShenSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lili QiuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Fangzheng YuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xiangyu HuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Min WangSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yan SunSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yihuai PanSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Keke ZhangSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-5755-7059
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: SCH-79797 was recently shown to be a broad-spectrum antibacterial agent with a dual-bactericidal mechanism. However, its anti-biofilm effect remains unknown. Purpose: To investigate the effect of SCH-79797 on the biofilm formation of the cariogenic Methods and Results: Crystal violet staining, colony forming units count and MTT assays (for cell metabolic activity) revealed that Conclusion: SCH-79797 had an anti-biofilm effect and showed application prospects in the control of dental caries.

Indexed as

biofilmscariogenic virulencedental cariesSCH-79797Streptococcus mutans

Identifiers

PMID35480051
PMCPMC9037171
OpenAlexW4224054879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.